Gene: NRAS ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease BEFREE All BRAF wild-type naevi (15%; n = 6/40) harboured an NRAS codon 12/13 or 61 mutation. 28714107 2018
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease BEFREE These findings document that common conjunctival melanocytic nevi have mutually exclusive mutations in BRAF and NRAS. 29332123 2018
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease BEFREE In vitro, 1 in 250 cells from fresh lCMN formed colonies that could be passaged and harbored the same NRAS mutation as the original nevus. 25310409 2015
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 Biomarker disease GENOMICS_ENGLAND Multilineage somatic activating mutations in HRAS and NRAS cause mosaic cutaneous and skeletal lesions, elevated FGF23 and hypophosphatemia. 24006476 2014
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease BEFREE Focused amplicon deep sequencing on DNA extracted from the brain tumor and a cutaneous nevus revealed a heterozygous (c.37G>C; p.G13R) substitution in the NRAS gene. 25330907 2014
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease BEFREE In this series the presence of a BRAF- or NRAS mutation in a nevus was not associated with the risk of malignant transformation. 23861977 2013
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 Biomarker disease GENOMICS_ENGLAND A restricted spectrum of NRAS mutations causes Noonan syndrome. 19966803 2010
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease BEFREE Both Spitz naevi and spitzoid melanoma had a lower combined BRAF and NRAS mutation frequency compared with common acquired naevi (P = 0.0001) and common forms of melanoma (P = 0.0072), respectively. 19438459 2009
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 Biomarker disease BEFREE Our results suggest that although nevus propensity is important for the occurrence of both BRAF and NRAS-mutant melanomas, ambient UV irradiance influences risk differently based on the age of exposure. 17507627 2007
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease BEFREE BRAF and NRAS mutations in melanoma and melanocytic nevi. 16845322 2006
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease LHGDN BRAF and NRAS mutations in melanoma and melanocytic nevi. 16845322 2006
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease BEFREE In addition, NRAS mutations were found in 2/11 (18.2%) CANs and 3/12 (25%) CMs. 15252839 2004
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 GeneticVariation disease BEFREE Our results suggest that mutations in the BRAF gene and to some extent in the N-ras gene represent early somatic events that occur in melanocytic nevi. 15009715 2004
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.500 Biomarker disease HPO