Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2
Gene Symbol: A2M
A2M 		0.010 AlteredExpression group LHGDN Binding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK. 15908432 2005
Entrez Id: 8086
Gene Symbol: AAAS
AAAS 		0.300 Biomarker group CTD_human The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. 24763052 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.070 AlteredExpression group BEFREE Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors. 11909640 2002
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.070 Biomarker group BEFREE Reactive oxygen species-linked regulation of the multidrug resistance transporter P-glycoprotein in Nox-1 overexpressing prostate tumor spheroids. 16083877 2005
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.070 Biomarker group BEFREE Redox regulation of P-glycoprotein-mediated multidrug resistance in multicellular prostate tumor spheroids. 10629088 2000
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.070 GeneticVariation group LHGDN ABCB1 genetic variation influences the toxicity and clinical outcome of patients with androgen-independent prostate cancer treated with docetaxel. 18628469 2008
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.070 AlteredExpression group BEFREE We hypothesize that early in prostate cancer progression, increased expression of YB-1 may increase P-gp activity which may in turn lower androgen levels in the prostate tumor cells. 15042610 2004
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.070 AlteredExpression group BEFREE Down-regulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by reactive oxygen species. 11279018 2001
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.070 GeneticVariation group BEFREE The MDR1 gene messenger ribonucleic acid (mRNA) was detected in two tumors using the Chinese hamster probe (one sphenoid wing meningioma and one metastatic prostate tumor) and in one CNS lymphoma using the human probe. 1682428 1991
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1 		0.010 Biomarker group LHGDN [Role of PTEN protein in multidrug resistance of prostate cancer cells]. 18702307 2008
Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4 		0.320 Biomarker group CTD_human Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774 2007
Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4 		0.320 Biomarker group LHGDN Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774 2007
Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4 		0.320 Biomarker group LHGDN Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer. 18615486 2008
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1 		0.010 GeneticVariation group LHGDN RNASEL and RNASEL-inhibitor variation and prostate cancer risk in Afro-Caribbeans. 18189233 2008
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.020 PosttranslationalModification group LHGDN The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells. 18056989 2008
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.020 Biomarker group LHGDN [Role of PTEN protein in multidrug resistance of prostate cancer cells]. 18702307 2008
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5 		0.300 Biomarker group CTD_human The Interaction between Pesticide Use and Genetic Variants Involved in Lipid Metabolism on Prostate Cancer Risk. 22919386 2012
Entrez Id: 10006
Gene Symbol: ABI1
ABI1 		0.010 AlteredExpression group BEFREE Moreover, ABI1 expression was significantly decreased in Gleason pattern 5 vs. pattern 4 (p = 0.0025) and 3 (p = 0.0012), indicating an association between low ABI1 expression and highly invasive prostate tumors. 31530281 2019
Entrez Id: 28
Gene Symbol: ABO
ABO 		0.300 Biomarker group CTD_human Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model. 17013881 2007
Entrez Id: 29
Gene Symbol: ABR
ABR 		0.310 Biomarker group CTD_human The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. 24763052 2014
Entrez Id: 29
Gene Symbol: ABR
ABR 		0.310 Biomarker group BEFREE Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors. 20470445 2010
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1 		0.010 AlteredExpression group LHGDN Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT). 18000807 2008
Entrez Id: 39
Gene Symbol: ACAT2
ACAT2 		0.010 AlteredExpression group LHGDN Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT). 18000807 2008
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.310 GeneticVariation group LHGDN Effects of ACE I/D polymorphism on prostate cancer risk, tumor grade and metastatis. 17465223 2007
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.310 Biomarker group CTD_human Effects of ACE I/D polymorphism on prostate cancer risk, tumor grade and metastatis. 17465223 2007