Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23299
Gene Symbol: BICD2
BICD2 		0.310 Biomarker disease GENOMICS_ENGLAND In-frame de novo mutation in BICD2 in two patients with muscular atrophy and arthrogryposis. 30054298 2018
Entrez Id: 406906
Gene Symbol: MIR122
MIR122 		0.200 Biomarker disease RGD Decreased expression of miR-122 in pterygium might result in abnormal cell apoptosis via its regulation of the expression of Bcl-w, and subsequently contribute to the development of pterygium. 27415790 2016
Entrez Id: 599
Gene Symbol: BCL2L2
BCL2L2 		0.200 Biomarker disease RGD Regulation of Apoptosis by miR-122 in Pterygium via Targeting Bcl-w. 27415790 2016
Entrez Id: 5352
Gene Symbol: PLOD2
PLOD2 		0.120 Biomarker disease HPO
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.110 Biomarker disease HPO
Entrez Id: 1643
Gene Symbol: DDB2
DDB2 		0.100 Biomarker disease HPO
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4 		0.100 Biomarker disease HPO
Entrez Id: 7507
Gene Symbol: XPA
XPA 		0.100 Biomarker disease HPO
Entrez Id: 7508
Gene Symbol: XPC
XPC 		0.100 Biomarker disease HPO
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.100 Biomarker disease BEFREE Elevated blood/lymphatic vessel ratio in pterygium and its relationship with vascular endothelial growth factor (VEGF) distribution. 30821336 2019
Entrez Id: 285489
Gene Symbol: DOK7
DOK7 		0.100 Biomarker disease HPO
Entrez Id: 2073
Gene Symbol: ERCC5
ERCC5 		0.100 Biomarker disease HPO
Entrez Id: 60681
Gene Symbol: FKBP10
FKBP10 		0.100 Biomarker disease HPO
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		0.100 Biomarker disease HPO
Entrez Id: 55505
Gene Symbol: NOP10
NOP10 		0.100 Biomarker disease HPO
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.100 Biomarker disease BEFREE We report on the presence of CTGF in pterygium and its simultaneous presence with vascular endothelial growth factor (VEGF). 12605268 2003
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.100 Biomarker disease BEFREE This study was designed to investigate the expression of low-density lipoprotein receptor (LDLr) stimulated by VEGF in PSFs. 28686975 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 Biomarker disease BEFREE VEGF and p53 proteins were found in all cases of primary pterygium in epithelial, fibroblast and vascular endothelial cells. 19481369 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.100 Biomarker disease BEFREE Use of anti-vascular endothelial growth factor in the management of pterygium. 27473792 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.100 Biomarker disease BEFREE In analysis of specimens from pterygium patients as well as normal conjunctivas, VEGF121 and VEGF165 were identified as the only VEGF splice forms expressed. 15885787 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 Biomarker disease BEFREE These studies indicate that tumor suppressor gene p53 and other genes associated with DNA repair, cell proliferation, migration and angiogenesis are critical for the development of pterygium. 24047084 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.100 Biomarker disease BEFREE Western blotting was used to compare amounts of p53 protein in pterygia and normal conjunctiva. 16005868 2006
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.100 Biomarker disease BEFREE VEGFA expression may have potential for use in the selective treatment of pterygium with anti-VEGFA agents. 20198298 2010
Entrez Id: 4323
Gene Symbol: MMP14
MMP14 		0.100 Biomarker disease HPO
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.100 Biomarker disease BEFREE In conclusion, the present study showed that COX-2 may play an important role in stimulating the angiogenesis of pterygium in concert with VEGF. 29285278 2017