Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.520 Biomarker disease CTD_human Preventive effect of TRPV1 agonists capsaicin and resiniferatoxin on ischemia/reperfusion-induced renal injury in rats. 18460982 2008
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Therapeutic disease CTD_human Cobalt protoporphyrin (CoPP) was administered IP at 10 or 20mg/kg 24h before IRI, to induce HO-1 upregulation.Control animals received vehicle alone. 17660127 2007
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Biomarker disease CTD_human Beneficial effect of heme oxygenase-1 expression on myocardial ischemia-reperfusion involves an increase in adiponectin in mildly diabetic rats. 17906103 2007
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Therapeutic disease CTD_human Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways. 25780291 2015
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Therapeutic disease CTD_human Inhibition of ischemia/reperfusion injury and chronic graft deterioration by a single-donor treatment with cobalt-protoporphyrin for the induction of heme oxygenase-1. 12352873 2002
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Biomarker disease CTD_human Resveratrol mitigates rat retinal ischemic injury: the roles of matrix metalloproteinase-9, inducible nitric oxide, and heme oxygenase-1. 23075401 2013
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Biomarker disease CTD_human Inhibition of ischemia/reperfusion injury and chronic graft deterioration by a single-donor treatment with cobalt-protoporphyrin for the induction of heme oxygenase-1. 12352873 2002
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Therapeutic disease CTD_human Beneficial effect of heme oxygenase-1 expression on myocardial ischemia-reperfusion involves an increase in adiponectin in mildly diabetic rats. 17906103 2007
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Biomarker disease CTD_human This study evaluated whether genetically decreased HO-1 levels affected susceptibility to liver IRI. 16982915 2006
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Biomarker disease CTD_human Cobalt protoporphyrin (CoPP) was administered IP at 10 or 20mg/kg 24h before IRI, to induce HO-1 upregulation.Control animals received vehicle alone. 17660127 2007
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Biomarker disease CTD_human Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways. 25780291 2015
Entrez Id: 6548
Gene Symbol: SLC9A1
SLC9A1 		0.510 Therapeutic disease CTD_human Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress? 19027022 2009
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.510 Biomarker disease CTD_human Resveratrol mitigates rat retinal ischemic injury: the roles of matrix metalloproteinase-9, inducible nitric oxide, and heme oxygenase-1. 23075401 2013
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Therapeutic disease CTD_human Resveratrol mitigates rat retinal ischemic injury: the roles of matrix metalloproteinase-9, inducible nitric oxide, and heme oxygenase-1. 23075401 2013
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Therapeutic disease CTD_human This study evaluated whether genetically decreased HO-1 levels affected susceptibility to liver IRI. 16982915 2006
Entrez Id: 4353
Gene Symbol: MPO
MPO 		0.500 Biomarker disease CTD_human Pulmonary nitric oxide metabolism following infrarenal aortic cross-clamp-induced ischaemia-reperfusion injury. 10706834 2000
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.500 Biomarker disease CTD_human Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. 16682413 2006
Entrez Id: 4353
Gene Symbol: MPO
MPO 		0.500 Biomarker disease CTD_human Glyceryl trinitrate prevents neutrophil activation but not thromboxane release following ischaemia-reperfusion injury. 8869312 1996
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5 		0.500 Biomarker disease CTD_human Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton. 15266012 2004
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.500 Therapeutic disease CTD_human Increased superoxide formation induced by irradiation preconditioning triggers kidney resistance to ischemia-reperfusion injury in mice. 19193722 2009
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.500 Therapeutic disease CTD_human Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. 16682413 2006
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.500 Therapeutic disease CTD_human Neutrophil and nonneutrophil-mediated injury in intestinal ischemia-reperfusion. 8215636 1993
Entrez Id: 4353
Gene Symbol: MPO
MPO 		0.500 Biomarker disease CTD_human Role of fenofibrate alone and in combination with telmisartan on renal ischemia/reperfusion injury. 20863214 2010
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.500 Biomarker disease CTD_human Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. 16682413 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.500 Biomarker disease CTD_human Endothelial dysfunction in rat mesenteric resistance artery after transient middle cerebral artery occlusion. 18258783 2008