Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3309
Gene Symbol: HSPA5
HSPA5 		0.200 Biomarker disease RGD 3-Bromo-7-nitroindazole attenuates brain ischemic injury in diabetic stroke via inhibition of endoplasmic reticulum stress pathway involving CHOP. 22075494 2012
Entrez Id: 3304
Gene Symbol: HSPA1B
HSPA1B 		0.200 Biomarker disease RGD Ischemia-reperfusion injury in the kidney is known to cause induction of the inducible form of the 70 kDa heat shock protein HSP70i (or HSP72). 10550516 1999
Entrez Id: 1839
Gene Symbol: HBEGF
HBEGF 		0.310 Biomarker disease LHGDN Heparin-binding EGF-like growth factor decreases inducible nitric oxide synthase and nitric oxide production after intestinal ischemia/reperfusion injury. 11761337 2001
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.320 AlteredExpression disease LHGDN Bcl-2 overexpression led to reduced cytochrome c-mediated caspase-9-dependent cardiomyocyte apoptosis and local inflammation (neutrophil infiltration and proinflammatory cytokine production) in cardiac allografts during ischemia-reperfusion injury and also led to reduced immune responses (inflammatory cell infiltration, production of T(H)1 cytokines and chemokines, and expression of adhesion molecules) during acute and chronic rejection without affecting host CD4(+) and CD8(+) cell responses in the spleen. 15280201 2004
Entrez Id: 23607
Gene Symbol: CD2AP
CD2AP 		0.200 Biomarker disease RGD CD2AP expression in a renal ischemia/reperfusion injury model and analysis of its related genes using overexpression and RNA interference technique. 16088078 2005
Entrez Id: 2056
Gene Symbol: EPO
EPO 		0.010 Biomarker disease LHGDN Erythropoietin protects the intestine against ischemia/ reperfusion injury in rats. 17873970 2007
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.320 Biomarker disease LHGDN Bcl-2 is known to inhibit apoptosis induced by the etiological factors promoting ischemia and reperfusion injury. 18468253 2008
Entrez Id: 5601
Gene Symbol: MAPK9
MAPK9 		0.300 Biomarker disease CTD_human Jnk-2 -/- animals were protected from hepatic ischemia reperfusion injury. 19667931 2009
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Therapeutic disease CTD_human Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways. 25780291 2015
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.510 Biomarker disease CTD_human Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways. 25780291 2015
Entrez Id: 6783
Gene Symbol: SULT1E1
SULT1E1 		0.500 Biomarker disease CTD_human Estrogen Sulfotransferase Is an Oxidative Stress-responsive Gene That Gender-specifically Affects Liver Ischemia/Reperfusion Injury. 25922074 2015
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2 		0.500 Biomarker disease RGD A novel ELR-CXC chemokine antagonist reduces intestinal ischemia reperfusion-induced mortality, and local and remote organ injury. 19691980 2010
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		0.200 Biomarker disease RGD A selective, non-peptide caspase-1 inhibitor, VRT-018858, markedly reduces brain damage induced by transient ischemia in the rat. 17845807 2007
Entrez Id: 2746
Gene Symbol: GLUD1
GLUD1 		0.200 Biomarker disease RGD Accumulation of ammonia and changes in the activity of some ammonia metabolizing enzymes during brain ischemia/reperfusion injury in rats. 7808037 1995
Entrez Id: 1464
Gene Symbol: CSPG4
CSPG4 		0.200 Biomarker disease RGD Accumulation of macrophage-like cells expressing NG2 proteoglycan and Iba1 in ischemic core of rat brain after transient middle cerebral artery occlusion. 17565360 2008
Entrez Id: 4314
Gene Symbol: MMP3
MMP3 		0.200 Biomarker disease RGD Activation of matrix metalloproteinase-3 and agrin cleavage in cerebral ischemia/reperfusion. 15099024 2004
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.200 Biomarker disease RGD Activation of peroxisome proliferator-activated receptor-alpha inhibits the injurious effects of adiponectin in rat steatotic liver undergoing ischemia-reperfusion. 18098300 2008
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A 		0.500 Biomarker disease RGD Adenosine A2A activation attenuates nontransplantation lung reperfusion injury. 17937935 2008
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A 		0.500 Therapeutic disease CTD_human Adenosine A2A and A2B Receptor Substantially Attenuate Ischemia/Reperfusion Injury in Septic rat Hearts. 27757725 2016
Entrez Id: 136
Gene Symbol: ADORA2B
ADORA2B 		0.300 Therapeutic disease CTD_human Adenosine A2A and A2B Receptor Substantially Attenuate Ischemia/Reperfusion Injury in Septic rat Hearts. 27757725 2016
Entrez Id: 133
Gene Symbol: ADM
ADM 		0.210 Biomarker disease RGD Adrenomedullin and adrenomedullin-binding protein-1 downregulate inflammatory cytokines and attenuate tissue injury after gut ischemia-reperfusion. 17263982 2007
Entrez Id: 133
Gene Symbol: ADM
ADM 		0.210 PosttranslationalModification disease LHGDN Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion. 12805025 2003
Entrez Id: 2903
Gene Symbol: GRIN2A
GRIN2A 		0.200 Biomarker disease RGD Age and meloxicam attenuate the ischemia/reperfusion-induced down-regulation in the NMDA receptor genes. 20350575 2010
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B 		0.200 Biomarker disease RGD Age and meloxicam attenuate the ischemia/reperfusion-induced down-regulation in the NMDA receptor genes. 20350575 2010
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.500 Therapeutic disease RGD Agmatine induces gastric protection against ischemic injury by reducing vascular permeability in rats. 22611311 2012