×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
CausalMutation
group
CGI
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population.
18482459
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain.
16870389
2006
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Association between CDH1 haplotypes and gastric cancer risk in a Japanese population.
17852867
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer.
12444556
2002
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
LHGDN
Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells.
17396032
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
CDH1 associated gastric cancer: a report of a family and review of the literature.
15780560
2005
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
CDH1/E-cadherin germline mutations in early-onset gastric cancer.
16801346
2006
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management.
16061854
2005
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
CTD_human
Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa.
19184424
2010
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
LHGDN
Clinical significance of dysadherin expression in gastric cancer patients.
15102690
2004
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
BEFREE
Despite advances with traditional single genes molecular research, including rare mutations in BRCA1/2 and CDH1 for primary prevention and trastuzumab for treating HER2-overexpressing breast and gastric tumors , overall, treatment failure and death rates are still alarmingly high.
20975737
2011
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
E-cadherin and hereditary diffuse gastric cancer.
17981184
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer.
12216071
2002
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
CTD_human
E-cadherin germline mutations in familial gastric cancer.
9537325
1998
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
AlteredExpression
group
LHGDN
Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells.
18377425
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer.
17545690
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
LHGDN
Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin.
16132582
2005
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
CTD_human
Germline CDH1 deletions in hereditary diffuse gastric cancer families.
19168852
2009
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
CTD_human
Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer.
10072428
1999
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Germline E-cadherin mutations in familial lobular breast cancer.
17660459
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria.
15235021
2004
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family.
17126523
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Hereditary diffuse gastric cancer: association with lobular breast cancer.
18046629
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
Biomarker
group
CTD_human
Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands.
12588804
2003