Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.070 | PosttranslationalModification | disease | BEFREE | There was a weak but statistically significant negative correlation between immunoreactivity of GPR30 and that of ER in cervical AIS and adenocarcinoma lesions (Spearman's correlation, r=-0.324, p=0.017). | 31483053 | 2019 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Adolescent idiopathic scoliosis (AIS) is reported to be associated with the two traditional estrogen receptor genes, ESR1 and ESR2. | 22002330 | 2012 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | To examine the association between AIS and estrogen receptor genes, we investigated the association of rs9340799 and rs1256120 with AIS predisposition and curve severity using a large Japanese population, consisting of 798 AIS patients and 637 sex-matched controls. | 21520258 | 2011 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Single nucleotide polymorphism (SNP) sites in the genes for estrogen receptor α (ERα), estrogen receptor β (ERβ), tryptophan hydroxylase 1 (TPH-1), melatonin receptor 1B (MTNR1B) and matrillin-1 (MATN1), which were previously identified to be predisposition genes for AIS, were selected for genotyping by the PCR-RFLP method. | 21691901 | 2011 | ||||
|
0.070 | Biomarker | disease | BEFREE | To investigate whether single nucleotide polymorphisms (SNP) of the calmodulin1 (CALM1) and estrogen receptor-α genes correlate with double curve in adolescent idiopathic scoliosis (AIS). | 22009847 | 2009 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | To investigate the association of estrogen receptor gene polymorphisms with adolescent idiopathic scoliosis (AIS) risk. | 16648749 | 2006 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | A common single nucleotide polymorphism (SNP) in ESR1 (XbaI) was found to be associated with curve severity in Japanese AIS patients recently. | 17023856 | 2006 |