Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2205
Gene Symbol: FCER1A
FCER1A 		0.310 Biomarker disease LHGDN Basophil phenotypes in chronic idiopathic urticaria in relation to disease activity and autoantibodies. 18356810 2008
Entrez Id: 2205
Gene Symbol: FCER1A
FCER1A 		0.310 Biomarker disease CTD_human Genetic markers for differentiating aspirin-hypersensitivity. 16502481 2006
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1 		0.310 Biomarker disease CTD_human Genetic markers for differentiating aspirin-hypersensitivity. 16502481 2006
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1 		0.310 Biomarker disease BEFREE In haplotype analysis, the HLA-DRB1(*)1302-DQB1(*)0609-DPB1(*)0201 was significantly higher in the aspirin-induced urticaria (8.0%) than in the aspirin-intolerant asthma (0.7%, P=0.0014) and normal controls (2.0%, P=0.0006). 15784113 2005
Entrez Id: 213
Gene Symbol: ALB
ALB 		0.310 Biomarker disease CTD_human Urticaria and angioedema during insemination with fluid containing bovine serum albumin. 8458210 1993
Entrez Id: 3176
Gene Symbol: HNMT
HNMT 		0.300 Biomarker disease CTD_human Genetic and ethnic risk factors associated with drug hypersensitivity. 20485159 2010
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker disease CTD_human Association between a TGFbeta1 promoter polymorphism and the phenotype of aspirin-intolerant chronic urticaria in a Korean population. 19138248 2008
Entrez Id: 4353
Gene Symbol: MPO
MPO 		0.300 Biomarker disease CTD_human Neutrophil activation in patients with ASA-induced urticaria. 18204966 2008
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.300 Biomarker disease CTD_human Familial aggregation of aspirin-induced urticaria and leukotriene C synthase allelic variant. 16433794 2006
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1 		0.300 Biomarker disease CTD_human Evaluation of inflammatory parameters in physical urticarias and effects of an anti-inflammatory/antiallergic treatment. 12121561 2002
Entrez Id: 6401
Gene Symbol: SELE
SELE 		0.300 Biomarker disease CTD_human Evaluation of inflammatory parameters in physical urticarias and effects of an anti-inflammatory/antiallergic treatment. 12121561 2002
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.300 Biomarker disease CTD_human Evaluation of inflammatory parameters in physical urticarias and effects of an anti-inflammatory/antiallergic treatment. 12121561 2002
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.160 GeneticVariation disease BEFREE The cryopyrin-associated periodic fever syndrome (CAPS) is an autosomal dominant autoinflammatory disorder caused by mutations in the NLRP3 gene and is typified by recurrent episodes of systemic inflammation resulting in fever, urticarial rash and arthralgia. 26931528 2016
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.160 GeneticVariation disease BEFREE Urticarial rash, one of the clinical manifestations characteristic of cryopyrin-associated periodic syndrome (CAPS), is caused by a mutation in the gene encoding for NLRP3 (nucleotide-binding oligomerization domain, leucine-rich repeats containing family, pyrin domain containing 3). 20179416 2010
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.160 Biomarker disease BEFREE Our findings implicate MCs as IL-1beta producers in the skin and mediators of histamine-independent urticaria through the NLRP3 inflammasome. 19364881 2009
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.160 Biomarker disease BEFREE Dominant mutations in the CIAS1 gene cause a spectrum of autoinflammatory diseases such as familial cold autoinflammatory syndrome, FCAS, which is characterized by episodes of urticaria, arthralgia, fever and conjunctivitis after generalized exposure to cold. 15245511 2004
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.160 GeneticVariation disease LHGDN Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. 12355493 2002
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.160 GeneticVariation disease LHGDN New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes. 11992256 2002
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.160 Biomarker disease HPO
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3 		0.110 AlteredExpression disease BEFREE No significant difference was detected in the expression levels of FOXP3 or TGF-beta between CU patients (n=14) and control subjects (n=7). 18440785 2008
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3 		0.110 Biomarker disease HPO
Entrez Id: 25890
Gene Symbol: ABI3BP
ABI3BP 		0.100 GeneticVariation disease GWASCAT Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations. 24236485 2013
Entrez Id: 112752
Gene Symbol: IFT43
IFT43 		0.100 GeneticVariation disease GWASCAT Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations. 24236485 2013
Entrez Id: 3815
Gene Symbol: KIT
KIT 		0.100 Biomarker disease HPO
Entrez Id: 58484
Gene Symbol: NLRC4
NLRC4 		0.100 Biomarker disease HPO