Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human Paroxetine for prevention of depressive symptoms induced by interferon-alpha and ribavirin for hepatitis C. 17451562 2007
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Therapeutic disease CTD_human Search for biological correlates of depression and mechanisms of action of antidepressant treatment modalities. Do neuropeptides play a role? 17572454 2007
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.300 Biomarker disease CTD_human Search for biological correlates of depression and mechanisms of action of antidepressant treatment modalities. Do neuropeptides play a role? 17572454 2007
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
0.300 Biomarker disease CTD_human Neuronal nitric oxide synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis. 17854383 2007
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
0.300 Biomarker disease CTD_human Up-regulation of tryptophan hydroxylase-2 mRNA in the rat brain by chronic fluoxetine treatment correlates with its antidepressant effect. 17950541 2007
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Biomarker disease CTD_human Adrenocorticotropic hormone and cortisol plasma levels directly correlate with childhood neglect and depression measures in addicted patients. 18201294 2008
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
0.300 Biomarker disease CTD_human Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects. 18286196 2008
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.310 Biomarker disease CTD_human Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. 18458677 2009
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.300 Biomarker disease CTD_human Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. 18458677 2009
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.310 Biomarker disease CTD_human The association between serotonin transporter gene promoter polymorphism (5-HTTLPR), self-reported symptoms, and dental mercury exposure. 18686203 2008
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.300 Biomarker disease CTD_human Continuous expression of corticotropin-releasing factor in the central nucleus of the amygdala emulates the dysregulation of the stress and reproductive axes. 18698320 2009
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.310 GeneticVariation disease BEFREE With a 2-year prospective study of a community sample (N = 521) of older people (aged 65+), information on baseline number of health complaints, diagnosis of moderate/severe depressive syndrome (Geriatric Mental State), and genotypes for 5-HTTLPR and MTHFR C677T polymorphisms were ascertained. 19251870 2009
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.310 GeneticVariation disease BEFREE With a 2-year prospective study of a community sample (N = 521) of older people (aged 65+), information on baseline number of health complaints, diagnosis of moderate/severe depressive syndrome (Geriatric Mental State), and genotypes for 5-HTTLPR and MTHFR C677T polymorphisms were ascertained. 19251870 2009
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.300 Biomarker disease CTD_human Ghrelin, paraoxonase and arylesterase levels in depressive patients before and after citalopram treatment. 19272368 2009
Entrez Id: 51738
Gene Symbol: GHRL
GHRL
0.300 Biomarker disease CTD_human Ghrelin, paraoxonase and arylesterase levels in depressive patients before and after citalopram treatment. 19272368 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.300 Biomarker disease CTD_human Chronic treatment with celecoxib reverses chronic unpredictable stress-induced depressive-like behavior via reducing cyclooxygenase-2 expression in rat brain. 19356723 2009
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.300 Biomarker disease CTD_human Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment. 19605942 2009
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human Factors influencing long-term changes in mental health after interferon-alpha treatment of chronic hepatitis C. 19691667 2009
Entrez Id: 4282
Gene Symbol: MIF
MIF
0.300 Biomarker disease CTD_human Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors. 20177408 2011
Entrez Id: 2931
Gene Symbol: GSK3A
GSK3A
0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. 20534517 2010
Entrez Id: 6281
Gene Symbol: S100A10
S100A10
0.300 Biomarker disease CTD_human Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression. 21682946 2012
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.310 Biomarker disease CTD_human Estradiol and progesterone modify the effects of the serotonin reuptake transporter polymorphism on serotonergic responsivity to citalopram. 21843009 2011
Entrez Id: 348
Gene Symbol: APOE
APOE
0.010 GeneticVariation disease BEFREE We were able to replicate the previous study, finding that, at least in East Asian origin populations, the APOE e4 allele is a stronger predictor of incident dementia in the presence of depressive syndrome, and particular depressive symptoms. 21845591 2011