Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.310 Biomarker disease CTD_human Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. 18458677 2009
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.300 Biomarker disease CTD_human Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. 18458677 2009
Entrez Id: 1129
Gene Symbol: CHRM2
CHRM2
0.020 GeneticVariation disease BEFREE Genet., 13, 1903-1911] reported that variation in CHRM2 gene predisposed to alcohol dependence (AD) and major depressive syndrome. 16000316 2005
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.300 Biomarker disease CTD_human Ghrelin, paraoxonase and arylesterase levels in depressive patients before and after citalopram treatment. 19272368 2009
Entrez Id: 51738
Gene Symbol: GHRL
GHRL
0.300 Biomarker disease CTD_human Ghrelin, paraoxonase and arylesterase levels in depressive patients before and after citalopram treatment. 19272368 2009
Entrez Id: 7038
Gene Symbol: TG
TG
0.300 Biomarker disease CTD_human Hashimoto's thyroiditis induces neuroinflammation and emotional alterations in euthyroid mice. 30373627 2018
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
0.300 Biomarker disease CTD_human Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder. 16861106 2006
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
0.300 Biomarker disease CTD_human Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder. 16861106 2006
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Therapeutic disease CTD_human Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801. 21945287 2012
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker disease CTD_human Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801. 21945287 2012
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.300 Biomarker disease CTD_human Intracerebroventricular corticotropin-releasing factor increases limbic glucose metabolism and has social context-dependent behavioral effects in nonhuman primates. 12438692 2002
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.300 Biomarker disease CTD_human Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment. 19605942 2009
Entrez Id: 213
Gene Symbol: ALB
ALB
0.300 Biomarker disease CTD_human Lower total serum protein, albumin, and beta- and gamma-globulin in major and treatment-resistant depression: effects of antidepressant treatments. 9029664 1996
Entrez Id: 4282
Gene Symbol: MIF
MIF
0.300 Biomarker disease CTD_human Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors. 20177408 2011
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.310 Biomarker disease CTD_human Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review. 17074966 2007
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 6616
Gene Symbol: SNAP25
SNAP25
0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 1816
Gene Symbol: DRD5
DRD5
0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 5649
Gene Symbol: RELN
RELN
0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
0.300 Biomarker disease CTD_human Neurobiochemical changes from Taxol/Neupogen chemotherapy for metastatic breast carcinoma corresponds with suicidal depression. 9018096 1996
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
0.300 Biomarker disease CTD_human Neuronal nitric oxide synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis. 17854383 2007
Entrez Id: 1312
Gene Symbol: COMT
COMT
0.310 Biomarker disease PSYGENET No correlation was found between the changes in COMT activity and the psychopathological picture of depression or the severity of endogenous depressive syndrome. 6846043 1983
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
0.300 Biomarker disease CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099 2011
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human Paroxetine for prevention of depressive symptoms induced by interferon-alpha and ribavirin for hepatitis C. 17451562 2007
Entrez Id: 6403
Gene Symbol: SELP
SELP
0.300 Biomarker disease CTD_human Platelet hyperactivity, neurobehavioral symptoms and depression among Indian women chronically exposed to low level of arsenic. 25451969 2014