×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.330
Biomarker
phenotype
CTD_human
The mRNA expressions of COX-2 and TNF -α genes were 3.13 and 2.31 folds higher in PTB cases in comparison to term delivery. l0 inear positive correlations were observed between period of gestation (POG) and ΔCt of COX-2 and TNF -α genes.
27748297
2016
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.330
GeneticVariation
phenotype
LHGDN
Two estimated TNFA haplotypes were associated with preterm birth with OR 3.1 (p=0.037) and OR 2.7 (p=0.045).
18951205
2008
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.330
GeneticVariation
phenotype
LHGDN
Risk of spontaneous preterm birth is associated with common proinflammatory cytokine polymorphisms.
15951664
2005
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.330
GeneticVariation
phenotype
LHGDN
The rarer of 2 alleles of a polymorphism in the promoter of the tumor necrosis factor alpha gene (TNF) has been associated with spontaneous preterm birth following preterm premature rupture of the fetal membranes in some populations.
15284722
2004
×
Entrez Id:
3565
Gene Symbol:
IL4
IL4
0.320
Biomarker
phenotype
CTD_human
Inflammatory-mediated pathway in association with organochlorine pesticides levels in the etiology of idiopathic preterm birth.
26055944
2015
×
Entrez Id:
3569
Gene Symbol:
IL6
IL6
0.320
Biomarker
phenotype
CTD_human
Inflammatory-mediated pathway in association with organochlorine pesticides levels in the etiology of idiopathic preterm birth.
26055944
2015
×
Entrez Id:
3569
Gene Symbol:
IL6
IL6
0.320
Biomarker
phenotype
LHGDN
Interleukin-6 (IL-6 ) and receptor (IL6 -R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth .
18276608
2008
×
Entrez Id:
3569
Gene Symbol:
IL6
IL6
0.320
GeneticVariation
phenotype
LHGDN
Risk of spontaneous preterm birth is associated with common proinflammatory cytokine polymorphisms.
15951664
2005
×
Entrez Id:
3565
Gene Symbol:
IL4
IL4
0.320
GeneticVariation
phenotype
LHGDN
Risk of small-for-gestational age is associated with common anti-inflammatory cytokine polymorphisms.
15951665
2005
×
Entrez Id:
3565
Gene Symbol:
IL4
IL4
0.320
GeneticVariation
phenotype
LHGDN
Interleukin-4 and -10 gene polymorphisms and spontaneous preterm birth in multifetal gestations.
15042002
2004
×
Entrez Id:
4968
Gene Symbol:
OGG1
OGG1
0.300
Biomarker
phenotype
CTD_human
This study investigated the associations of OGG1 Ser326Cys SNP in relation to HIV and obesity on the susceptibility of low-birthweight (LBW) and pre-term birth (PTB) in SA women exposed to ambient air-pollution living in Durban.
29709520
2018
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
0.300
Biomarker
phenotype
CTD_human
The mRNA expressions of COX-2 and TNF-α genes were 3.13 and 2.31 folds higher in PTB cases in comparison to term delivery. l0 inear positive correlations were observed between period of gestation (POG) and ΔCt of COX-2 and TNF-α genes.
27748297
2016
×
Entrez Id:
847
Gene Symbol:
CAT
CAT
0.300
Biomarker
phenotype
CTD_human
Inflammatory-mediated pathway in association with organochlorine pesticides levels in the etiology of idiopathic preterm birth.
26055944
2015
×
Entrez Id:
1906
Gene Symbol:
EDN1
EDN1
0.300
Biomarker
phenotype
CTD_human
BQ-123 prevents LPS-induced preterm birth in mice via the induction of uterine and placental IL-10.
25230003
2015
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
0.300
Biomarker
phenotype
CTD_human
Inflammatory-mediated pathway in association with organochlorine pesticides levels in the etiology of idiopathic preterm birth.
26055944
2015
×
Entrez Id:
6648
Gene Symbol:
SOD2
SOD2
0.300
Biomarker
phenotype
CTD_human
Inflammatory-mediated pathway in association with organochlorine pesticides levels in the etiology of idiopathic preterm birth.
26055944
2015
×
Entrez Id:
4318
Gene Symbol:
MMP9
MMP9
0.300
Biomarker
phenotype
CTD_human
Matrix metalloproteinase (MMP) 9 plays an important role in the degradation of the extracellular matrix in fetal membranes, and pathological activation of MMP-9 can lead to preterm birth .
24429678
2014
×
Entrez Id:
4153
Gene Symbol:
MBL2
MBL2
0.300
Biomarker
phenotype
CTD_human
Our data add to the knowledge about genetic predisposition to prematurity and suggest that the fetal MBL2 genotype might be an additional genetic factor contributing to the risk of premature delivery .
16912583
2006
×
Entrez Id:
4057
Gene Symbol:
LTF
LTF
0.300
Therapeutic
phenotype
CTD_human
Therapeutic potential of iron chelators in diseases associated with iron mismanagement.
16640825
2006
×
Entrez Id:
64135
Gene Symbol:
IFIH1
IFIH1
0.100
CausalMutation
phenotype
CLINVAR
An extremely severe case of Aicardi-Goutières syndrome 7 with a novel variant in IFIH1.
30965144
2020
×
Entrez Id:
196883
Gene Symbol:
ADCY4
ADCY4
0.100
GeneticVariation
phenotype
GWASCAT
Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8.
29538362
2018
MICOS10-NBL1
0.100
GeneticVariation
phenotype
GWASCAT
Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants.
30113228
2018
×
Entrez Id:
54971
Gene Symbol:
BANP
BANP
0.100
GeneticVariation
phenotype
GWASCAT
Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8.
29538362
2018
×
Entrez Id:
4681
Gene Symbol:
NBL1
NBL1
0.100
GeneticVariation
phenotype
GWASCAT
Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants.
30113228
2018
×
Entrez Id:
513
Gene Symbol:
ATP5F1D
ATP5F1D
0.100
CausalMutation
phenotype
CLINVAR
Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder.
29478781
2018