Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
0.100 GeneticVariation disease GWASCAT Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. 28044437 2017
Entrez Id: 7486
Gene Symbol: WRN
WRN
0.100 Biomarker disease HPO
Entrez Id: 6794
Gene Symbol: STK11
STK11
0.100 Biomarker disease HPO
Entrez Id: 324
Gene Symbol: APC
APC
0.100 Biomarker disease HPO
Entrez Id: 10673
Gene Symbol: TNFSF13B
TNFSF13B
0.010 Biomarker disease BEFREE Our results therefore indicate a potential role for fecal BAFF as a sensitive screening parameter for IBD and gastrointestinal carcinoma, as well a useful tool to select patients with abdominal discomfort for further endoscopic examinations. 31314927 2019
Entrez Id: 4233
Gene Symbol: MET
MET
0.010 Biomarker disease BEFREE Gastrointestinal Carcinoma with Plasmacytoid Morphology: Positivity for c-MET, Arylsulfatase, and Markers of Epithelial-Mesenchymal Transition, as Indicators of Aggressivity. 31205468 2019
Entrez Id: 1025
Gene Symbol: CDK9
CDK9
0.010 Biomarker disease BEFREE TAK-264 (MLN0264) in Previously Treated Asian Patients with Advanced Gastrointestinal Carcinoma Expressing Guanylyl Cyclase C: Results from an Open-Label, Non-randomized Phase 1 Study. 28494535 2018
Entrez Id: 2984
Gene Symbol: GUCY2C
GUCY2C
0.010 GeneticVariation disease BEFREE TAK-264 (MLN0264) in Previously Treated Asian Patients with Advanced Gastrointestinal Carcinoma Expressing Guanylyl Cyclase C: Results from an Open-Label, Non-randomized Phase 1 Study. 28494535 2018
Entrez Id: 5351
Gene Symbol: PLOD1
PLOD1
0.010 AlteredExpression disease BEFREE These results indicated that PLOD1 is highly expressed in gastrointestinal carcinoma and is a potential prognostic marker and therapeutic target. 29723071 2018
Entrez Id: 7503
Gene Symbol: XIST
XIST
0.010 AlteredExpression disease BEFREE Our results showed that expression level of XIST was markedly associated with overall survival (function as oncogene, HR = 0.53, 95% CI: 0.42-0.68, <i>p</i> < 0.00001; function as tumor suppressor, HR = 2.25, 95% CI: 1.15-4.37, <i>p</i> = 0.02), disease free survival (DFS)(HR = 0.45; 95% CI: 0.31-0.67, <i>p</i> < 0.0001), tumor type (digestive system carcinoma, HR = 0.50; 95% CI: 0.37-0.69, <i>p</i> < 0.00001; non-digestive system carcinoma, HR = 0.58; 95% CI: 0.39-0.87, <i>p</i> = 0.008), lymph node metastasis (OR = 0.32, 95% CI: 0.20-0.52, <i>p</i> < 0.00001), distant metastasis (OR = 0.36, 95% CI: 0.22-0.60, <i>p</i> < 0.0001) and tumor stage (OR = 0.43, 95% CI: 0.31-0.60, <i>p</i> < 0.00001). 29568404 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.010 Biomarker disease BEFREE This study aimed to determine the influence of proton pump inhibitors that exhibit an inhibitory effect on P-glycoprotein in gastrointestinal carcinoma cell lines, namely Caco-2 and LS174T, in relation to H. pylori adherence. 27991853 2017
Entrez Id: 2526
Gene Symbol: FUT4
FUT4
0.010 AlteredExpression disease BEFREE In this study, we screened for major variations of sialyltransferases and fucosyltransferases involved in the synthesis and regulation of sialyl Lewis x and sialyl Lewis a epitopes in gastrointestinal carcinoma cells. 19781661 2010
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.010 AlteredExpression disease BEFREE Gastrointestinal carcinoma cell lines were examined for cell scattering activity in response to LPA, and the expression of LPA receptor subtypes was determined by RT-PCR. 18592268 2009
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
0.010 AlteredExpression disease BEFREE VEGFR-1 and VEGFR-3 expression was detected in all the gastrointestinal carcinoma cells evaluated. 19755510 2009
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
0.010 AlteredExpression disease BEFREE The homeodomain transcription factor CDX2 is a relatively specific immunohistochemical marker for gastrointestinal carcinoma. 19584150 2009
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
0.010 AlteredExpression disease BEFREE VEGFR-1 and VEGFR-3 expression was detected in all the gastrointestinal carcinoma cells evaluated. 19755510 2009
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
0.010 Biomarker disease BEFREE We used a chemotherapy scheme based on 5-FU for the treatment of 75 patients with gastrointestinal carcinoma and detected the serum drug concentration and DPYD gene polymorphism (DPYD*2, *3, *4 *5 *9 *12). 17848752 2007
Entrez Id: 1087
Gene Symbol: CEACAM7
CEACAM7
0.010 Biomarker disease BEFREE Only one blood sample from patients with no gastrointestinal carcinoma was positive for CEA mRNA. 12684893 2003
Entrez Id: 5670
Gene Symbol: PSG2
PSG2
0.010 Biomarker disease BEFREE Only one blood sample from patients with no gastrointestinal carcinoma was positive for CEA mRNA. 12684893 2003
Entrez Id: 1084
Gene Symbol: CEACAM3
CEACAM3
0.010 Biomarker disease BEFREE Only one blood sample from patients with no gastrointestinal carcinoma was positive for CEA mRNA. 12684893 2003
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
0.010 Biomarker disease BEFREE Only one blood sample from patients with no gastrointestinal carcinoma was positive for CEA mRNA. 12684893 2003
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.010 Biomarker disease BEFREE Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines. 14525978 2003
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.010 AlteredExpression disease BEFREE The GA733-2 antigen is a cell surface glycoprotein highly expressed on most human gastrointestinal carcinoma and at a lower level on most normal epithelia. 11080501 2001
Entrez Id: 3621
Gene Symbol: ING1
ING1
0.010 Biomarker disease BEFREE When we examined the sequence of p33(ING1) in 12 gastrointestinal carcinoma cell lines, we found mutation in only one cell line, HCT116. 10660101 1999
Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
0.010 Biomarker disease BEFREE Similarities of in situ mRNA expression between gelatinase A (MMP-2) and type I procollagen in human gastrointestinal carcinoma: comparison with granulation tissue reaction. 7591960 1995