Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1 		0.020 GeneticVariation disease BEFREE To assess the effect of maternal CYP2D6, CYP3A5, ABCB1, and OPRM1 polymorphisms in predicting both neonatal and maternal central nervous system depression after oxycodone use during lactation. 23783165 2013
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.020 GeneticVariation disease BEFREE The ABCB1 2677 T variant may predict oxycodone-induced central nervous system depression in breastfeeding mothers. 23783165 2013
Entrez Id: 7364
Gene Symbol: UGT2B7
UGT2B7 		0.020 Biomarker disease BEFREE We aimed to discover the genetic markers predictive of codeine toxicity by evaluating the associations between polymorphisms in cytochrome P450 2D6 (CYP2D6), UDP-glucuronosyltransferase 2B7 (UGT2B7), P-glycoprotein (ABCB1), mu-opioid receptor (OPRM1), and catechol O-methyltransferase (COMT) genes, which are involved in the codeine pathway, and the symptoms of CNS depression in 111 breastfeeding mothers using codeine and their infants. 22398969 2012
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1 		0.020 Biomarker disease BEFREE We aimed to discover the genetic markers predictive of codeine toxicity by evaluating the associations between polymorphisms in cytochrome P450 2D6 (CYP2D6), UDP-glucuronosyltransferase 2B7 (UGT2B7), P-glycoprotein (ABCB1), mu-opioid receptor (OPRM1), and catechol O-methyltransferase (COMT) genes, which are involved in the codeine pathway, and the symptoms of CNS depression in 111 breastfeeding mothers using codeine and their infants. 22398969 2012
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.020 Biomarker disease BEFREE We aimed to discover the genetic markers predictive of codeine toxicity by evaluating the associations between polymorphisms in cytochrome P450 2D6 (CYP2D6), UDP-glucuronosyltransferase 2B7 (UGT2B7), P-glycoprotein (ABCB1), mu-opioid receptor (OPRM1), and catechol O-methyltransferase (COMT) genes, which are involved in the codeine pathway, and the symptoms of CNS depression in 111 breastfeeding mothers using codeine and their infants. 22398969 2012
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		0.020 GeneticVariation disease BEFREE We aimed to discover the genetic markers predictive of codeine toxicity by evaluating the associations between polymorphisms in cytochrome P450 2D6 (CYP2D6), UDP-glucuronosyltransferase 2B7 (UGT2B7), P-glycoprotein (ABCB1), mu-opioid receptor (OPRM1), and catechol O-methyltransferase (COMT) genes, which are involved in the codeine pathway, and the symptoms of CNS depression in 111 breastfeeding mothers using codeine and their infants. 22398969 2012
Entrez Id: 7364
Gene Symbol: UGT2B7
UGT2B7 		0.020 Biomarker disease BEFREE Breastfed infants of mothers who are CYP2D6 UMs combined with the UGT2B7*2/*2 are at increased risk of potentially life-threatening CNS depression. 18719619 2009
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		0.020 Biomarker disease BEFREE Breastfed infants of mothers who are CYP2D6 UMs combined with the UGT2B7*2/*2 are at increased risk of potentially life-threatening CNS depression. 18719619 2009
Entrez Id: 107987479
Gene Symbol: LOC107987479
LOC107987479 		0.010 GeneticVariation disease BEFREE We aimed to discover the genetic markers predictive of codeine toxicity by evaluating the associations between polymorphisms in cytochrome P450 2D6 (CYP2D6), UDP-glucuronosyltransferase 2B7 (UGT2B7), P-glycoprotein (ABCB1), mu-opioid receptor (OPRM1), and catechol O-methyltransferase (COMT) genes, which are involved in the codeine pathway, and the symptoms of CNS depression in 111 breastfeeding mothers using codeine and their infants. 22398969 2012
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.010 Biomarker disease BEFREE We aimed to discover the genetic markers predictive of codeine toxicity by evaluating the associations between polymorphisms in cytochrome P450 2D6 (CYP2D6), UDP-glucuronosyltransferase 2B7 (UGT2B7), P-glycoprotein (ABCB1), mu-opioid receptor (OPRM1), and catechol O-methyltransferase (COMT) genes, which are involved in the codeine pathway, and the symptoms of CNS depression in 111 breastfeeding mothers using codeine and their infants. 22398969 2012