Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		0.040 Biomarker disease BEFREE Increased frequencies at p<0.01 were found for antibodies to p16 in breast, esophageal, and nasopharyngeal cancer as well as HCC. 17016600 2006
Entrez Id: 108004545
Gene Symbol: LOC108004545
LOC108004545 		0.030 Biomarker disease BEFREE NCSCs were enriched from human nasopharyngeal cancer cell lines CNE2 and HONE1 through tumorsphere-forming assay. 31342620 2019
Entrez Id: 108004545
Gene Symbol: LOC108004545
LOC108004545 		0.030 Biomarker disease BEFREE Overexpression of miR-29 causes decrease in the viability of CNE2 nasopharyngeal cancer cells via induction of apoptosis and autophagy. 31298371 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.030 Biomarker disease BEFREE To co-deliver hydrophobic drug and functional gene efficiently into tumor cells, a star-shaped copolymer (PP-PLLD-Arg) with a photochemical internalization effect consisting of a porphyrin (PP) core and arginine-functionalized poly(L-lysine) dendron (PLLD-Arg) arms has been designed, and used to co-deliver docetaxel (DOC) and MMP-9 shRNA plasmid for nasopharyngeal cancer therapy. 24576804 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.030 Biomarker disease BEFREE FLNA expression decreased in nasopharyngeal cancer and correlated significantly lymph node metastasis, clinic stage, histological grade, and poor overall survival, suggesting that FLNA may play important roles as a negative regulator to nasopharyngeal cancer CNE2 cell by promoting degradation of MMP-9. 24218340 2014
Entrez Id: 108004545
Gene Symbol: LOC108004545
LOC108004545 		0.030 Biomarker disease BEFREE It also exhibited antiproliferative activity on a number of tumor cells including MCF7 (breast cancer), HepG2 (liver cancer), CNE1 and CNE2 (nasopharyngeal cancer) cells, with stronger activity toward MCF7 and CNE1 cells. 23514011 2013
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.030 AlteredExpression disease BEFREE Hypericin photoactivation triggers down-regulation of matrix metalloproteinase-9 expression in well-differentiated human nasopharyngeal cancer cells. 17385073 2007
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		0.020 Biomarker disease BEFREE There was evidence to support the use of FDG PET/MRI in staging of nasopharyngeal cancer and high-risk BC. 31267161 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.020 Biomarker disease BEFREE LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy. 31410015 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.020 GeneticVariation disease BEFREE Contribution of Matrix Metalloproteinase-2 Promoter Genotypes to Nasopharyngeal Cancer Susceptibility and Metastasis in Taiwan. 31243109 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.020 Biomarker disease BEFREE Construction, Expression, and Characterization of rSEA-EGF and In Vitro Evaluation of its Antitumor Activity Against Nasopharyngeal Cancer. 29551087 2018
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7 		0.020 Biomarker disease BEFREE Although LMP1 is one of the latent genes required for EBV-immortalization of B cells, the biology of LMP1 in the pathogenesis of the epithelial cancer nasopharyngeal carcinoma (NPC) is more complex. 29561768 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.020 Biomarker disease BEFREE A Meta-Analysis of Vascular Endothelial Growth Factor for Nasopharyngeal Cancer Prognosis. 30430078 2018
Entrez Id: 406982
Gene Symbol: MIR20A
MIR20A 		0.020 Biomarker disease BEFREE MiR-20a-5p promotes radio-resistance by targeting Rab27B in nasopharyngeal cancer cells. 28265202 2017
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.020 Biomarker disease BEFREE MicroRNA-92b inhibits epithelial-mesenchymal transition-induced migration and invasion by targeting Smad3 in nasopharyngeal cancer. 29207670 2017
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		0.020 Biomarker disease BEFREE <sup>18</sup>FDG PET/PET-CT is superior to BS for diagnosing bone metastases in nasopharyngeal cancer patients.<sup>18</sup>FDG PET/PET-CT may enhance the diagnosis of bone metastases and provide more accurate information for the optimal management of nasopharyngeal cancer. 28938677 2017
Entrez Id: 406982
Gene Symbol: MIR20A
MIR20A 		0.020 Biomarker disease BEFREE MiR-20a-5p promotes radio-resistance by targeting NPAS2 in nasopharyngeal cancer cells. 29285299 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		0.020 Biomarker disease BEFREE STAT3 mediates resistance to anoikis and promotes invasiveness of nasopharyngeal cancer cells. 28949390 2017
Entrez Id: 406937
Gene Symbol: MIR145
MIR145 		0.020 Biomarker disease BEFREE Our previous studies have shown that miR-203 and miR-145 are associated with cellular invasion in NSCLC and nasopharyngeal cancer, respectively. 27237033 2016
Entrez Id: 406937
Gene Symbol: MIR145
MIR145 		0.020 Biomarker disease BEFREE miR-145 inhibits invasion and metastasis by directly targeting Smad3 in nasopharyngeal cancer. 25578496 2015
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1 		0.020 AlteredExpression disease BEFREE Correlation between ERCC1 expression and concurrent chemotherapy and radiotherapy in patients with locally advanced nasopharyngeal cancer. 26125779 2015
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.020 Biomarker disease BEFREE miR-145 inhibits invasion and metastasis by directly targeting Smad3 in nasopharyngeal cancer. 25578496 2015
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.020 Biomarker disease BEFREE Preclinical evaluation of the mTOR-PI3K inhibitor BEZ235 in nasopharyngeal cancer models. 24041865 2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.020 Biomarker disease BEFREE Preclinical evaluation of the mTOR-PI3K inhibitor BEZ235 in nasopharyngeal cancer models. 24041865 2014
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		0.020 Biomarker disease BEFREE Preclinical evaluation of the mTOR-PI3K inhibitor BEZ235 in nasopharyngeal cancer models. 24041865 2014