Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA 		0.300 SomaticCausalMutation disease ORPHANET Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma. 27647909 2016
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B 		0.200 Biomarker disease RGD HSP70 and mucin 5B: novel protein targets of N,N'-dinitrosopiperazine-induced nasopharyngeal tumorigenesis. 19068094 2009
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.060 AlteredExpression disease BEFREE However, no significant associations of p16 expression with the overall survival and progression-free survival of nasopharynx cancer were found. 30882625 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.060 AlteredExpression disease BEFREE Is human papillomavirus and p16 expression associated with survival outcomes in nasopharyngeal cancer?: A systematic review and meta-analysis. 30029797 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.060 Biomarker disease BEFREE The aim of this study was to compare different staging system models proposed for HPV-related OPC patients: 7th edition AJCC TNM, RPA stage with non-anatomic factors (Princess Margaret), RPA with N categories for nasopharyngeal cancer (MD-Anderson) and AHR-new (ICON-S), according to different HPV-relatedness definitions: HPV-DNA detection plus an additional positive marker (p16INK4a or HPV-mRNA), p16INK4a positivity alone or the combination of HPV-DNA/p16INK4a positivity as diagnostic tests. 29664911 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.060 Biomarker disease BEFREE P16 INK4A status predicts better outcome in laryngeal, hypopharyngeal or nasopharyngeal cancer cases treated with surgery plus adjuvant radiochemotherapy as well as with definitive radiation therapy and/or chemotherapy. 25640361 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.060 AlteredExpression disease BEFREE EZH2 regulates the expression of p16 in the nasopharyngeal cancer cells. 23289480 2013
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.060 Biomarker disease BEFREE Increased frequencies at p<0.01 were found for antibodies to p16 in breast, esophageal, and nasopharyngeal cancer as well as HCC. 17016600 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.050 GeneticVariation disease BEFREE Association between the P53 codon 72 polymorphism and nasopharyngeal cancer risk. 24114013 2014
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.050 GeneticVariation disease BEFREE Significant associations between GSTM1/GSTT1 polymorphisms and nasopharyngeal cancer risk. 23275251 2013
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.050 GeneticVariation disease BEFREE Meta-analysis of GSTM1 and GSTT1 polymorphisms and risk of nasopharyngeal cancer. 23679259 2013
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.050 GeneticVariation disease BEFREE Association between GSTM1 polymorphism and nasopharyngeal cancer susceptibility: a meta-analysis. 23317262 2012
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.050 GeneticVariation disease BEFREE Polymorphisms in GSTM1, GSTTI and GSTP1 and nasopharyngeal cancer in the east of China: a case-control study. 22393996 2011
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.050 GeneticVariation disease BEFREE GSTM1 and GSTT1 polymorphisms and nasopharyngeal cancer risk: an evidence-based meta-analysis. 19338664 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.050 GeneticVariation disease BEFREE TP53 codon 72 polymorphism contributes to nasopharyngeal cancer susceptibility: a meta-analysis. 19608020 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.050 GeneticVariation disease BEFREE We evaluated the linkage of the polymorphic variants (Arg/Pro) on TP53 codon 72 with nasopharyngeal cancer development in a case-control study with 392 individuals from a northern Portuguese population, including 107 patients with nasopharyngeal carcinoma and 285 healthy controls. 16835507 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.050 GeneticVariation disease BEFREE Although point mutations in the p53 gene are observed in nasopharyngeal cancer, the mutation rate is lower than in other tumors. 15523893 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.050 GeneticVariation disease BEFREE Three p53 DNA polymorphisms (BstUI and MspI RFLPs in exon 4 and intron 6, respectively, and a 16-bp duplication in intron 3) and their haplotype combinations were studied in 73 patients (61 males and 12 females) with nasopharyngeal cancer and 105 healthy controls from the Guizhou province in southern China. 8825463 1996
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		0.040 AlteredExpression disease BEFREE Is human papillomavirus and p16 expression associated with survival outcomes in nasopharyngeal cancer?: A systematic review and meta-analysis. 30029797 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		0.040 AlteredExpression disease BEFREE However, no significant associations of p16 expression with the overall survival and progression-free survival of nasopharynx cancer were found. 30882625 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.040 GeneticVariation disease BEFREE Significant associations between GSTM1/GSTT1 polymorphisms and nasopharyngeal cancer risk. 23275251 2013
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.040 GeneticVariation disease BEFREE Meta-analysis of GSTM1 and GSTT1 polymorphisms and risk of nasopharyngeal cancer. 23679259 2013
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		0.040 AlteredExpression disease BEFREE EZH2 regulates the expression of p16 in the nasopharyngeal cancer cells. 23289480 2013
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.040 GeneticVariation disease BEFREE The study was performed to assess the potential role of GSTM1, GSTT1 and GSTP1 polymorphisms in the risk of nasopharyngeal cancer in Chinese population. 22393996 2011
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.040 GeneticVariation disease BEFREE GSTM1 and GSTT1 polymorphisms and nasopharyngeal cancer risk: an evidence-based meta-analysis. 19338664 2009