Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE Variation in the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) gene plays a significant role in determining susceptibility to autoimmune thyroid disease and type 1 diabetes. 16325273 2006
Entrez Id: 7038
Gene Symbol: TG
TG 		0.100 GeneticVariation disease BEFREE Association of a rare thyroglobulin gene microsatellite variant with autoimmune thyroid disease. 14557492 2003
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE A common CTLA4 polymorphism confers susceptibility to autoimmune thyroid disease in celiac children. 18929517 2009
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE Increasing evidence supports the genetic susceptibility for thyroid antibody (TAb) production in patients with autoimmune thyroid disease, and recently, it has been shown that the cytotoxic T lymphocyte antigen 4 (CTLA-4) gene is most likely a major TAb susceptibility gene. 12097196 2002
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE Association of CTLA-4 gene A/G polymorphism in Japanese type 1 diabetic patients with younger age of onset and autoimmune thyroid disease. 10895849 2000
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE No evidence for allelic association of a human CTLA-4 promoter polymorphism with autoimmune thyroid disease in either population-based case-control or family-based studies. 9861324 1998
Entrez Id: 7038
Gene Symbol: TG
TG 		0.100 GeneticVariation disease BEFREE Association between thyroglobulin polymorphisms and autoimmune thyroid disease: a systematic review and meta-analysis of case-control studies. 30139952 2019
Entrez Id: 7038
Gene Symbol: TG
TG 		0.100 GeneticVariation disease BEFREE The thyroglobulin gene: the third locus for autoimmune thyroid disease or a false dawn? 15242676 2004
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.100 GeneticVariation disease BEFREE Three of the TSH receptor mutants, deletions of residues 295-306 and 387-395 and the point mutation of cysteine 301 to serine, are shown to be particularly useful in these assays and may be useful to clarify the pathogenetic role and clinical significance of stimulating TSHRAbs in patients with autoimmune thyroid disease who also have blocking TSHRAbs. 8100829 1993
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE Association of autoimmune thyroid disease with microsatellite markers for the thyrotropin receptor gene and CTLA-4 in Japanese patients. 11081251 2000
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.100 GeneticVariation disease BEFREE Association between thyroid stimulating hormone receptor gene intron polymorphisms and autoimmune thyroid disease in a Chinese Han population. 22673349 2012
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE The objective of this study was to examine the polymorphism in the cytotoxic T lymphocyte antigen-4 (CTLA-4) gene and its relationship with autoimmune thyroid disease in Koreans. 10907987 2000
Entrez Id: 7038
Gene Symbol: TG
TG 		0.100 GeneticVariation disease BEFREE Common allelic variants of exons 10, 12, and 33 of the thyroglobulin gene are not associated with autoimmune thyroid disease in the United Kingdom. 15579800 2004
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.100 GeneticVariation disease BEFREE A polymorphism in the extracellular domain of the thyrotropin receptor is highly associated with autoimmune thyroid disease in females. 7544179 1995
Entrez Id: 7038
Gene Symbol: TG
TG 		0.100 GeneticVariation disease BEFREE Association of the thyroglobulin gene polymorphism with autoimmune thyroid disease in Chinese population. 19034705 2008
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE 49A/G and CT60 polymorphisms of the cytotoxic T-lymphocyte-associated antigen 4 gene associated with autoimmune thyroid disease. 19559744 2009
Entrez Id: 7038
Gene Symbol: TG
TG 		0.100 GeneticVariation disease BEFREE Association of the polymorphisms in the gene encoding thyroglobulin with the development and prognosis of autoimmune thyroid disease. 28675712 2017
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE Association of the CTLA-4 gene 49 A/G polymorphism with type 1 diabetes and autoimmune thyroid disease in Japanese children. 12610047 2003
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.100 GeneticVariation disease BEFREE Association of autoimmune thyroid disease with microsatellite markers for the thyrotropin receptor gene and CTLA-4 in Japanese patients. 11081251 2000
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE Association of Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Gene Polymorphisms with Autoimmune Thyroid Disease in Children and Adults: Case-Control Study. 27111218 2016
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE The association of CTLA4 polymorphism with type 1 diabetes is concentrated in patients complicated with autoimmune thyroid disease: a multicenter collaborative study in Japan. 16352685 2006
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE Interaction of HLA-DRB1* alleles and CTLA4 (+49 AG) gene polymorphism in Autoimmune Thyroid Disease. 29174716 2018
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE CTLA-4 and autoimmune thyroid disease: lack of influence of the A49G signal peptide polymorphism on functional recombinant human CTLA-4. 12202150 2002
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.100 GeneticVariation disease BEFREE Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis. 17504905 2007
Entrez Id: 7038
Gene Symbol: TG
TG 		0.100 GeneticVariation disease BEFREE Correlation between thyroglobulin gene polymorphisms and autoimmune thyroid disease. 26099577 2015