Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5617
Gene Symbol: PRL
PRL 		0.300 Biomarker disease CTD_human [Morphological changes in prolactinoma induced by bromocriptine treatment]. 2274009 1991
Entrez Id: 2697
Gene Symbol: GJA1
GJA1 		0.300 Biomarker disease CTD_human Altered expression of connexins in urethane-induced mouse lung adenomas. 16926031 2006
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.300 Biomarker disease CTD_human Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice. 10426811 1999
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP 		0.300 Biomarker disease CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336 2008
Entrez Id: 6948
Gene Symbol: TCN2
TCN2 		0.300 Biomarker disease CTD_human Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the Nurses' Health Study. 17389618 2007
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.300 Biomarker disease CTD_human More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats. 10965019 2000
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1 		0.300 Biomarker disease CTD_human Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice. 11376689 2001
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human Neonatal exposure to the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine via breast milk or directly induces intestinal tumors in multiple intestinal neoplasia mice. 10383901 1999
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5 		0.300 Biomarker disease CTD_human Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model. 18927292 2008
Entrez Id: 3762
Gene Symbol: KCNJ5
KCNJ5 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D 		0.300 Biomarker disease CTD_human Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism. 23913001 2013
Entrez Id: 2705
Gene Symbol: GJB1
GJB1 		0.300 Biomarker disease CTD_human Altered expression of connexins in urethane-induced mouse lung adenomas. 16926031 2006
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer. 30188895 2018
Entrez Id: 3762
Gene Symbol: KCNJ5
KCNJ5 		0.300 Biomarker disease CTD_human Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism. 23913001 2013
Entrez Id: 54822
Gene Symbol: TRPM7
TRPM7 		0.300 Biomarker disease CTD_human The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. 17823441 2007
Entrez Id: 494337
Gene Symbol: MIR425
MIR425 		0.300 Biomarker disease CTD_human mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice. 25926378 2016
Entrez Id: 4763
Gene Symbol: NF1
NF1 		0.300 Biomarker disease CTD_human PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies. 25119042 2014
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.300 Biomarker disease CTD_human Lung cancer susceptibility in Fhit-deficient mice is increased by Vhl haploinsufficiency. 16061637 2005
Entrez Id: 442910
Gene Symbol: MIR345
MIR345 		0.300 Biomarker disease CTD_human mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice. 25926378 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.300 Biomarker disease CTD_human Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene. 10545420 1999
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.300 Biomarker disease CTD_human The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling. 25851810 2015
Entrez Id: 23600
Gene Symbol: AMACR
AMACR 		0.300 Biomarker disease CTD_human Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma. 17684125 2007
Entrez Id: 492
Gene Symbol: ATP2B3
ATP2B3 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension. 23416519 2013
Entrez Id: 4968
Gene Symbol: OGG1
OGG1 		0.010 Biomarker disease BEFREE It is concluded that deletion of hOGG1 gene occurs commonly in PRCC and CC-RCC but not in renal cortical PA. Further studies are warranted to further explore the exact roles of hOGG1 gene in the development and progression of RCC. 18477212 2008