Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer. 30188895 2018
Entrez Id: 574456
Gene Symbol: MIR497
MIR497 		0.300 Biomarker disease CTD_human mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice. 25926378 2016
Entrez Id: 406936
Gene Symbol: MIR144
MIR144 		0.300 Biomarker disease CTD_human mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice. 25926378 2016
Entrez Id: 494337
Gene Symbol: MIR425
MIR425 		0.300 Biomarker disease CTD_human mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice. 25926378 2016
Entrez Id: 442910
Gene Symbol: MIR345
MIR345 		0.300 Biomarker disease CTD_human mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice. 25926378 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.300 Biomarker disease CTD_human The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling. 25851810 2015
Entrez Id: 23512
Gene Symbol: SUZ12
SUZ12 		0.300 Biomarker disease CTD_human PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies. 25119042 2014
Entrez Id: 4763
Gene Symbol: NF1
NF1 		0.300 Biomarker disease CTD_human PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies. 25119042 2014
Entrez Id: 476
Gene Symbol: ATP1A1
ATP1A1 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013
Entrez Id: 489
Gene Symbol: ATP2A3
ATP2A3 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013
Entrez Id: 476
Gene Symbol: ATP1A1
ATP1A1 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension. 23416519 2013
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013
Entrez Id: 3762
Gene Symbol: KCNJ5
KCNJ5 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D 		0.300 Biomarker disease CTD_human Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism. 23913001 2013
Entrez Id: 3762
Gene Symbol: KCNJ5
KCNJ5 		0.300 Biomarker disease CTD_human Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism. 23913001 2013
Entrez Id: 492
Gene Symbol: ATP2B3
ATP2B3 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension. 23416519 2013
Entrez Id: 9049
Gene Symbol: AIP
AIP 		0.300 Biomarker disease CTD_human Aryl-hydrocarbon receptor activity modulates prolactin expression in the pituitary. 22975028 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.300 Biomarker disease CTD_human A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. 21946351 2011
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.300 Biomarker disease CTD_human Downregulation of breast cancer resistance protein in colon adenomas reduces cellular xenobiotic resistance and leads to accumulation of a food-derived carcinogen. 21544799 2011
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human Crypt stem cells as the cells-of-origin of intestinal cancer. 19092804 2009
Entrez Id: 7296
Gene Symbol: TXNRD1
TXNRD1 		0.300 Biomarker disease CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336 2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP 		0.300 Biomarker disease CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336 2008
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5 		0.300 Biomarker disease CTD_human Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model. 18927292 2008
Entrez Id: 4552
Gene Symbol: MTRR
MTRR 		0.300 Biomarker disease CTD_human Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the Nurses' Health Study. 17389618 2007
Entrez Id: 6573
Gene Symbol: SLC19A1
SLC19A1 		0.300 Biomarker disease CTD_human Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. 16963246 2007