Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7431
Gene Symbol: VIM
VIM
0.040 AlteredExpression disease BEFREE <b>Methods:</b> E-cadherin, Slug, Twist and Vimentin levels were detected by immunohistochemistry in 167 TNBC tumors, including 145 invasive carcinomas of no special type (ICONSTs), 14 spindle cell carcinomas (SpCCs) and 8 matrix-producing carcinomas (MPCs). 29483966 2018
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.010 GeneticVariation disease BEFREE Sarcomatoid carcinoma of the upper urinary tract is an aggressive tumor and the presence of TERT mutation may portend poor prognosis. 28052688 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.370 GeneticVariation disease BEFREE Spindle cell carcinomas lacked TP53 mutations, in contrast to other subtypes (78%, p = 0.003). 29946183 2018
Entrez Id: 3342
Gene Symbol: HTC2
HTC2
0.010 Biomarker disease BEFREE CGH analysis may help distinguish a cytokeratin-positive SM from a sarcomatoid carcinoma. 16170537 2006
Entrez Id: 6615
Gene Symbol: SNAI1
SNAI1
0.010 AlteredExpression disease BEFREE Snail protein expression level was positively correlated with pathological tumor stage, histological grade and the presence of sarcomatoid carcinoma. 21808237 2011
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.010 AlteredExpression disease BEFREE IGF-1R expression in non-small cell lung carcinoma was observed in 41.4% of samples and was more prevalent in SCC (69.3%) than in ADC (25.1%), large cell carcinoma (33.3%), and sarcomatoid carcinoma (12.2%) (P < .001). 23266446 2013
Entrez Id: 238
Gene Symbol: ALK
ALK
0.030 Biomarker disease BEFREE ALK rearrangement was observed in a single case of sarcomatoid carcinoma (3%), which has currently available targeted therapy. 27174587 2016
Entrez Id: 55272
Gene Symbol: IMP3
IMP3
0.010 AlteredExpression disease BEFREE IMP3 expression was identified in 7 cases of SPC (64%) and 6 patients of all the other subtypes (p=0.051). 29146055 2017
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.040 Biomarker disease BEFREE PD-L1 immunopositivity in TC or IC did not correlate with age, sex, stage or mutation status however sarcomatoid carcinoma and solid predominant adenocarcinomas showed higher positivity rates. 29146060 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.360 GeneticVariation disease BEFREE KRAS mutation is predictive of outcome in patients with pulmonary sarcomatoid carcinoma. 29489023 2018
Entrez Id: 110806263
Gene Symbol: LOC110806263
LOC110806263
0.010 GeneticVariation disease BEFREE TERT promoter mutations were enriched (47%) in spindle cell carcinomas and tumors with squamous or spindle/squamous differentiation. 29946183 2018
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.040 AlteredExpression disease BEFREE PD-L1 and CD47 co-expression in pulmonary sarcomatoid carcinoma: a predictor of poor prognosis and potential targets of future combined immunotherapy. 31522278 2019
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
0.300 Biomarker disease CTD_human A dominant negative mutation of transforming growth factor-beta receptor type II gene in microsatellite stable oesophageal carcinoma. 10789724 2000
Entrez Id: 4233
Gene Symbol: MET
MET
0.340 GeneticVariation disease BEFREE A KIF5B-MET fusion variant in a patient with a mixed-type adenocarcinoma and sarcomatoid tumor was identified, and another case was found in a pulmonary sarcomatoid carcinoma patient. 30015159 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.370 AlteredExpression disease BEFREE Abnormalities in tumor suppressor gene p53 expression also were found in two of the 11 SpCC cases using monoclonal antibody PAb 1801. 8276377 1993
Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST
0.300 Biomarker disease CTD_human Allelic imbalance and altered expression of genes in chromosome 2q11-2q16 from rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 12606953 2003
Entrez Id: 5921
Gene Symbol: RASA1
RASA1
0.300 Biomarker disease CTD_human Allelic imbalance and altered expression of genes in chromosome 2q11-2q16 from rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 12606953 2003
Entrez Id: 902
Gene Symbol: CCNH
CCNH
0.300 Biomarker disease CTD_human Allelic imbalance and altered expression of genes in chromosome 2q11-2q16 from rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 12606953 2003
Entrez Id: 5924
Gene Symbol: RASGRF2
RASGRF2
0.300 Biomarker disease CTD_human Allelic imbalance and altered expression of genes in chromosome 2q11-2q16 from rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 12606953 2003
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
0.300 Biomarker disease CTD_human Allelic imbalance and altered expression of genes in chromosome 2q11-2q16 from rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 12606953 2003
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
0.300 Biomarker disease CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778 2011
Entrez Id: 23643
Gene Symbol: LY96
LY96
0.300 Biomarker disease CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778 2011
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.300 Biomarker disease CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.370 GeneticVariation disease BEFREE Alteration of the p53 gene of lung carcinomas with sarcomatous transformation (spindle cell carcinoma): analysis of four cases. 10846548 1996
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
0.300 Biomarker disease CTD_human Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice. 10426811 1999