Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7270
Gene Symbol: TTF1
TTF1
0.020 AlteredExpression disease BEFREE Seventy-five % of PSCGCC were considered as positive for PD-L1.PD-L1 expression in PSGSCC is associated with TTF-1 and/or Napsin A expression (47.2%, p = 0.039). 28671973 2017
Entrez Id: 7270
Gene Symbol: TTF1
TTF1
0.020 Biomarker disease BEFREE We performed immunohistochemistry on 35 PSCGCs against TTF1, napsin A, p40, ALK, ROS1, and c-MET. 26826416 2016
Entrez Id: 5713
Gene Symbol: PSMD7
PSMD7
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 9181
Gene Symbol: ARHGEF2
ARHGEF2
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.010 AlteredExpression disease BEFREE Seventy-five % of PSCGCC were considered as positive for PD-L1.PD-L1 expression in PSGSCC is associated with TTF-1 and/or Napsin A expression (47.2%, p = 0.039). 28671973 2017
Entrez Id: 115482699
Gene Symbol: H3P28
H3P28
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 339541
Gene Symbol: ARMH1
ARMH1
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 10244
Gene Symbol: RABEPK
RABEPK
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 10314
Gene Symbol: LANCL1
LANCL1
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 3578
Gene Symbol: IL9
IL9
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 3921
Gene Symbol: RPSA
RPSA
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 10969
Gene Symbol: EBNA1BP2
EBNA1BP2
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1
0.010 AlteredExpression disease BEFREE Seventy-five % of PSCGCC were considered as positive for PD-L1.PD-L1 expression in PSGSCC is associated with TTF-1 and/or Napsin A expression (47.2%, p = 0.039). 28671973 2017
Entrez Id: 8626
Gene Symbol: TP63
TP63
0.010 Biomarker disease BEFREE Few p40 positive PSCGCC expressed PD-L1 (8.3%, p = 0.013). 28671973 2017
Entrez Id: 9476
Gene Symbol: NAPSA
NAPSA
0.010 AlteredExpression disease BEFREE Seventy-five % of PSCGCC were considered as positive for PD-L1.PD-L1 expression in PSGSCC is associated with TTF-1 and/or Napsin A expression (47.2%, p = 0.039). 28671973 2017
Entrez Id: 238
Gene Symbol: ALK
ALK
0.010 AlteredExpression disease BEFREE No PSCGC (0/4) with only squamous cell or adenosquamous (0/2) differentiation was mutated. c-MET overexpression was only seen in PSCGC with adenocarcinomatous or undifferentiated component (n = 5) without squamous cell component.ROS1 and ALK were negative. 26826416 2016
Entrez Id: 4233
Gene Symbol: MET
MET
0.010 AlteredExpression disease BEFREE No PSCGC (0/4) with only squamous cell or adenosquamous (0/2) differentiation was mutated. c-MET overexpression was only seen in PSCGC with adenocarcinomatous or undifferentiated component (n = 5) without squamous cell component.ROS1 and ALK were negative. 26826416 2016
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
0.010 AlteredExpression disease BEFREE No PSCGC (0/4) with only squamous cell or adenosquamous (0/2) differentiation was mutated. c-MET overexpression was only seen in PSCGC with adenocarcinomatous or undifferentiated component (n = 5) without squamous cell component.ROS1 and ALK were negative. 26826416 2016
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
0.010 GeneticVariation disease LHGDN Therefore, mutated TGFBR2 seems to play an important role in the abrogation of TGFB signal transduction in GCC cells. 17117417 2007
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.010 GeneticVariation disease BEFREE Rearrangement of the c-myc gene in two giant cell carcinomas of the lung. 3093421 1986
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.010 Biomarker disease BEFREE Giant cell carcinomas of the lung producing colony-stimulating factor in vitro and in vivo. 3935627 1985