Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.200 Therapeutic phenotype CTD_mouse Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics. 28193520 2017
Entrez Id: 133
Gene Symbol: ADM
ADM 		0.300 Biomarker phenotype CTD_human A role for adrenomedullin as a pain-related peptide in the rat. 17043245 2006
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		0.300 Biomarker phenotype CTD_human Activation of protein kinase B/Akt in the periphery contributes to pain behavior induced by capsaicin in rats. 17084039 2007
Entrez Id: 213
Gene Symbol: ALB
ALB 		0.300 Therapeutic phenotype CTD_human Clofibrate, nephrotic syndrome, and histological changes in muscle. 4126124 1973
Entrez Id: 358
Gene Symbol: AQP1
AQP1 		0.300 Biomarker phenotype CTD_human Aquaporin-1 tunes pain perception by interaction with Na(v)1.8 Na+ channels in dorsal root ganglion neurons. 20018876 2010
Entrez Id: 551
Gene Symbol: AVP
AVP 		0.300 Therapeutic phenotype CTD_human Phenylephrine-induced antinociception: investigations of potential neural and endocrine bases. 2271928 1990
Entrez Id: 551
Gene Symbol: AVP
AVP 		0.300 Therapeutic phenotype CTD_human Pain threshold changes in rats following central injection of beta-endorphin, met-enkephalin, vasopressin or oxytocin antisera. 6094376 1984
Entrez Id: 113451
Gene Symbol: AZIN2
AZIN2 		0.010 Biomarker phenotype BEFREE Clinically, ADC gel does not have any side effects and discomfort such as pain, burning, tingling sensation or numbness and produces no adverse reactions in time. 31663443 2020
Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1 		0.300 Biomarker phenotype CTD_human Kinin B1 receptors contributes to acute pain following minor surgery in humans. 20152050 2010
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2 		0.300 Biomarker phenotype CTD_human Kinin B1 receptors contributes to acute pain following minor surgery in humans. 20152050 2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.010 Biomarker phenotype BEFREE Involvement of brain-derived neurotrophic factor (BDNF) in chronic intermittent stress-induced enhanced mechanical allodynia in a rat model of burn pain. 31014242 2019
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1 		0.300 Biomarker phenotype CTD_human Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin. 17088553 2006
Entrez Id: 1268
Gene Symbol: CNR1
CNR1 		0.300 Therapeutic phenotype CTD_human CB1 receptors mediate the analgesic effects of cannabinoids on colorectal distension-induced visceral pain in rodents. 19193902 2009
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.300 Biomarker phenotype CTD_human Disruption of thermal nociceptive behaviour in mice mutant for the schizophrenia-associated genes NRG1, COMT and DISC1. 20561508 2010
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Therapeutic phenotype CTD_human Analgesia and hyperalgesia from CRF receptor modulation in the central nervous system of Fischer and Lewis rats. 16495007 2006
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		0.300 Biomarker phenotype CTD_human Severe atypical neuropathy associated with administration of hematopoietic colony-stimulating factors and vincristine. 8622042 1996
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		0.300 Biomarker phenotype CTD_human Severe atypical neuropathy associated with administration of hematopoietic colony-stimulating factors and vincristine. 8622042 1996
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		0.300 Biomarker phenotype CTD_human Astemizole in the treatment of granulocyte colony-stimulating factor-induced bone pain. 7541186 1995
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		0.300 Biomarker phenotype CTD_human Combined administration of G-CSF and dexamethasone for the mobilization of granulocytes in normal donors: optimization of dosing. 10864982 2000
Entrez Id: 27185
Gene Symbol: DISC1
DISC1 		0.300 Biomarker phenotype CTD_human Disruption of thermal nociceptive behaviour in mice mutant for the schizophrenia-associated genes NRG1, COMT and DISC1. 20561508 2010
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human Influence of the dopamine D2 receptor knockout on pain-related behavior in the mouse. 15996639 2005
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.300 Biomarker phenotype CTD_human Involvement of TRPA1 in ET-1-induced pain-like behavior in mice. 20042899 2010
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.300 Biomarker phenotype CTD_human Role of ET(A) and ET(B) endothelin receptors on endothelin-1-induced potentiation of nociceptive and thermal hyperalgesic responses evoked by capsaicin in rats. 19429182 2009
Entrez Id: 339896
Gene Symbol: GADL1
GADL1 		0.010 Biomarker phenotype BEFREE Clinically, ADC gel does not have any side effects and discomfort such as pain, burning, tingling sensation or numbness and produces no adverse reactions in time. 31663443 2020
Entrez Id: 2596
Gene Symbol: GAP43
GAP43 		0.010 GeneticVariation phenotype BEFREE Our clinical and skin biopsy study showed that ongoing burning pain was strongly associated with regenerating sprouts, as assessed with GAP43 immunostaining. 29885017 2018