Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2593
Gene Symbol: GAMT
GAMT 		0.300 Biomarker disease CTD_human Guanidinoacetate methyltransferase deficiency identified in adults and a child with mental retardation. 15651030 2005
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Biomarker disease CTD_human ACTH-induced seizures in an infant with West syndrome. 2554740 1989
Entrez Id: 3630
Gene Symbol: INS
INS 		0.300 Biomarker disease CTD_human Drug-induced convulsions. Report from Boston Collaborative Drug Surveillance Program. 4115818 1972
Entrez Id: 6854
Gene Symbol: SYN2
SYN2 		0.300 Biomarker disease CTD_human Genetic deletion of synapsin II reduces neuropathic pain due to reduced glutamate but increased GABA in the spinal cord dorsal horn. 18701217 2008
Entrez Id: 2572
Gene Symbol: GAD2
GAD2 		0.300 Biomarker disease CTD_human Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures. 8985701 1996
Entrez Id: 10280
Gene Symbol: SIGMAR1
SIGMAR1 		0.300 Biomarker disease CTD_human Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters. 11684152 2001
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B 		0.300 Biomarker disease CTD_human The role of the central serotonergic system in pilocarpine-induced seizures: receptor mechanisms. 2533336 1989
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4 		0.300 Biomarker disease CTD_human The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice. 15275829 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker disease CTD_human Dopamine D1 and D2 receptors mediate opposite functions in seizures induced by lithium-pilocarpine. 1829682 1991
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Therapeutic disease CTD_human Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. 16194568 2005
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker disease CTD_human Some endorphin derivatives and hydrocortisone prevent EEG limbic seizures induced by corticotropin-releasing factor in rabbits. 1700951 1991
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker disease CTD_human HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 27083141 2016
Entrez Id: 249
Gene Symbol: ALPL
ALPL 		0.300 Biomarker disease CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Biomarker disease CTD_human [A case of Aicardi syndrome with moderate psychomotor retardation]. 2169275 1990
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.300 Biomarker disease CTD_human Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine. 12432978 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker disease CTD_human Dopamine D2 receptor signaling controls neuronal cell death induced by muscarinic and glutamatergic drugs. 11860278 2002
Entrez Id: 5173
Gene Symbol: PDYN
PDYN 		0.300 Therapeutic disease CTD_human [The role of the opiate mechanisms of the hippocampus and substantia nigra in the behavioral and convulsive disorders in picrotoxin-induced kindling]. 1675896 1991
Entrez Id: 54805
Gene Symbol: CNNM2
CNNM2 		0.300 Biomarker disease CTD_human Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2). 23027747 2012
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker disease CTD_human C-Fos expression as a molecular marker in corticotropin-releasing factor-induced seizures. 8923670 1996
Entrez Id: 4504
Gene Symbol: MT3
MT3 		0.300 Biomarker disease CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker disease CTD_human Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. 16194568 2005
Entrez Id: 4804
Gene Symbol: NGFR
NGFR 		0.300 Biomarker disease CTD_human p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure. 10436046 1999
Entrez Id: 7779
Gene Symbol: SLC30A1
SLC30A1 		0.300 Biomarker disease CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.300 Biomarker disease CTD_human Pharmacological inhibition of inducible nitric oxide synthase attenuates the development of seizures in mice. 19559095 2009
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		0.300 Biomarker disease CTD_human Mutational analysis of GLUT1 (SLC2A1) in Glut-1 deficiency syndrome. 10980529 2000