Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 18
Gene Symbol: ABAT
ABAT 		0.300 Biomarker disease CTD_human 4-Aminobutyrate aminotransferase (GABA-transaminase) deficiency. 10407778 1999
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.200 Biomarker disease CTD_mouse Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. 17437408 2007
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2 		0.300 Biomarker disease CTD_human Expression of the multidrug transporter MRP2 in the blood-brain barrier after pilocarpine-induced seizures in rats. 16504477 2006
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1 		0.300 Biomarker disease CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker disease CTD_human HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 27083141 2016
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker disease CTD_human Pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats. 19941057 2010
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Therapeutic disease CTD_human HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 27083141 2016
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Therapeutic disease CTD_human Pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats. 19941057 2010
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1 		0.300 Biomarker disease CTD_human IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings. 29673861 2018
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A 		0.300 Biomarker disease CTD_human Adenosine A2A receptor deficient mice are partially resistant to limbic seizures. 19488739 2009
Entrez Id: 147
Gene Symbol: ADRA1B
ADRA1B 		0.300 Biomarker disease CTD_human Lack of alpha 1b-adrenergic receptor protects against epileptic seizures. 19125850 2009
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Biomarker disease CTD_human Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. 16771832 2006
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		0.300 Biomarker disease CTD_human Lipoic acid alters delta-aminolevulinic dehydratase, glutathione peroxidase and Na+,K+-ATPase activities and glutathione-reduced levels in rat hippocampus after pilocarpine-induced seizures. 19798568 2010
Entrez Id: 5832
Gene Symbol: ALDH18A1
ALDH18A1 		0.010 Biomarker disease BEFREE Recently, we reported a newly recognised inborn error due to deficiency of P5CS in two sibs, one presenting at birth with hypotonia, dysmorphic signs, pes planus and clonic seizures. 15517380 2005
Entrez Id: 249
Gene Symbol: ALPL
ALPL 		0.300 Biomarker disease CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 249
Gene Symbol: ALPL
ALPL 		0.300 Therapeutic disease CTD_human Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6. 7550313 1995
Entrez Id: 249
Gene Symbol: ALPL
ALPL 		0.300 Therapeutic disease CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 249
Gene Symbol: ALPL
ALPL 		0.300 Biomarker disease CTD_human Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6. 7550313 1995
Entrez Id: 328
Gene Symbol: APEX1
APEX1 		0.300 Biomarker disease CTD_human Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures. 20446108 2010
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A 		0.300 Biomarker disease CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746 2012
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Therapeutic disease CTD_human Efficacy of human serum butyrylcholinesterase against sarin vapor. 18597747 2008
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Therapeutic disease CTD_human Administration of purified human plasma cholinesterase protects against cocaine toxicity in mice. 8667461 1996
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Therapeutic disease CTD_human Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine. 20971807 2011
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.300 Therapeutic disease CTD_human Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. 9073163 1997