Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 387
Gene Symbol: RHOA
RHOA 		0.300 Biomarker phenotype CTD_human Postzygotic inactivating mutations of RHOA cause a mosaic neuroectodermal syndrome. 31570889 2019
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A 		0.300 Biomarker phenotype CTD_human PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal. 29367455 2018
Entrez Id: 23476
Gene Symbol: BRD4
BRD4 		0.300 Biomarker phenotype CTD_human Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition. 25242322 2014
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.300 Biomarker phenotype CTD_human Hairless modulates ligand-dependent activation of the vitamin D receptor-retinoid X receptor heterodimer. 22466564 2012
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human CRF receptor antagonist astressin-B reverses and prevents alopecia in CRF over-expressing mice. 21359208 2011
Entrez Id: 54503
Gene Symbol: ZDHHC13
ZDHHC13 		0.300 Biomarker phenotype CTD_human Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. 20548961 2010
Entrez Id: 142
Gene Symbol: PARP1
PARP1 		0.300 Biomarker phenotype CTD_human Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1. 20561897 2010
Entrez Id: 6832
Gene Symbol: SUPV3L1
SUPV3L1 		0.300 Biomarker phenotype CTD_human Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. 19145458 2009
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A 		0.300 Biomarker phenotype CTD_human Mapatumumab, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: results of a phase I and pharmacokinetic study. 19652058 2009
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.300 Biomarker phenotype CTD_human Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. 18381794 2008
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2 		0.300 Biomarker phenotype CTD_human Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. 18381794 2008
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2 		0.300 Biomarker phenotype CTD_human 5alpha-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia. 17136762 2007
Entrez Id: 55806
Gene Symbol: HR
HR 		0.300 Biomarker phenotype CTD_human A novel missense mutation in the mouse hairless gene causes irreversible hair loss: genetic and molecular analyses of Hr m1Enu. 16455232 2006
Entrez Id: 367
Gene Symbol: AR
AR 		0.300 Biomarker phenotype CTD_human Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia. 15902657 2005
Entrez Id: 7538
Gene Symbol: ZFP36
ZFP36 		0.300 Biomarker phenotype CTD_human Structure/function analysis of tristetraprolin (TTP): p38 stress-activated protein kinase and lipopolysaccharide stimulation do not alter TTP function. 15944294 2005
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.300 Biomarker phenotype CTD_human [Vitamin D-resistant rickets type II: apropos of 2 cases]. 1338926 1992