Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6310
Gene Symbol: ATXN1
ATXN1 		0.300 Biomarker group CTD_human Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress. 28182653 2017
Entrez Id: 6904
Gene Symbol: TBCD
TBCD 		0.300 Biomarker group CTD_human Biallelic Mutations in TBCD, Encoding the Tubulin Folding Cofactor D, Perturb Microtubule Dynamics and Cause Early-Onset Encephalopathy. 27666370 2016
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.300 Biomarker group CTD_human shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model. 26075822 2015
Entrez Id: 6709
Gene Symbol: SPTAN1
SPTAN1 		0.300 Biomarker group CTD_human Initial biological qualification of SBDP-145 as a biomarker of compound-induced neurodegeneration in the rat. 25015659 2014
Entrez Id: 5311
Gene Symbol: PKD2
PKD2 		0.300 Biomarker group CTD_human Systemic treatment with erythropoietin protects the neurovascular unit in a rat model of retinal neurodegeneration. 25013951 2014
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker group CTD_human Trientine reduces BACE1 activity and mitigates amyloidosis via the AGE/RAGE/NF-κB pathway in a transgenic mouse model of Alzheimer's disease. 23541064 2013
Entrez Id: 3060
Gene Symbol: HCRT
HCRT 		0.300 Biomarker group CTD_human Lead-induced neurodegenerative events and abnormal behaviors occur via ORXRergic/GABA(A)Rergic mechanisms in a marine teleost. 23246865 2013
Entrez Id: 4803
Gene Symbol: NGF
NGF 		0.300 Therapeutic group CTD_human Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. 24244623 2013
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker group CTD_human Trientine reduces BACE1 activity and mitigates amyloidosis via the AGE/RAGE/NF-κB pathway in a transgenic mouse model of Alzheimer's disease. 23541064 2013
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.300 Biomarker group CTD_human A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. 22430071 2012
Entrez Id: 5413
Gene Symbol: SEPTIN5
SEPTIN5 		0.300 Biomarker group CTD_human A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. 22430071 2012
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker group CTD_human A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. 22430071 2012
Entrez Id: 9118
Gene Symbol: INA
INA 		0.300 Biomarker group CTD_human A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. 22430071 2012
Entrez Id: 54902
Gene Symbol: TTC19
TTC19 		0.300 Biomarker group CTD_human Mutations in TTC19 cause mitochondrial complex III deficiency and neurological impairment in humans and flies. 21278747 2011
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B 		0.300 Biomarker group CTD_human Autosomal-dominant striatal degeneration is caused by a mutation in the phosphodiesterase 8B gene. 20085714 2010
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.300 Biomarker group CTD_human Acetaminophen attenuates dopamine neuron degeneration in animal models of Parkinson's disease. 18514411 2008
Entrez Id: 347
Gene Symbol: APOD
APOD 		0.300 Therapeutic group CTD_human Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila. 18458334 2008
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.300 Biomarker group CTD_human Adult-onset neurodegeneration with brain iron accumulation and cortical alpha-synuclein and tau pathology: a distinct clinicopathological entity. 17296847 2007
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.300 Therapeutic group CTD_human SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. 17581637 2007
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		0.300 Biomarker group CTD_human Art, alpha-1-antitrypsin polymorphisms and intense creative energy: blessing or curse? 17659342 2007
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.300 Therapeutic group CTD_human SIRT1 activation confers neuroprotection in experimental optic neuritis. 17652729 2007
Entrez Id: 80025
Gene Symbol: PANK2
PANK2 		0.300 Biomarker group CTD_human Adult-onset neurodegeneration with brain iron accumulation and cortical alpha-synuclein and tau pathology: a distinct clinicopathological entity. 17296847 2007
Entrez Id: 7431
Gene Symbol: VIM
VIM 		0.300 Biomarker group CTD_human Cell death pathways differ in several mouse models with motoneurone disease: analysis of pure motoneurone populations at a presymptomatic age. 16831193 2006
Entrez Id: 3620
Gene Symbol: IDO1
IDO1 		0.300 Biomarker group CTD_human Gene expression changes by amyloid beta peptide-stimulated human postmortem brain microglia identify activation of multiple inflammatory processes. 16365156 2006
Entrez Id: 80025
Gene Symbol: PANK2
PANK2 		0.300 Biomarker group CTD_human Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation. 16450344 2006