Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1729
Gene Symbol: DIAPH1
DIAPH1 		0.120 Biomarker disease BEFREE In addition to Wolfram syndrome gene 1 (DFNA6/14/38) and diaphanous (DFNA1) there is evidence for a third gene involved in low-frequency hearing loss located at DFNA15. 15490091 2004
Entrez Id: 1729
Gene Symbol: DIAPH1
DIAPH1 		0.120 Biomarker disease BEFREE Unusual phenotypes in autosomal dominant forms of deafness, include low frequency hearing loss in DFNA1 (HDIA1) and DFNA6/14/38 (WFS1), mid-frequency hearing loss in DFNA8/12 (TECTA), DFNA13 (COL11A2) and vestibular symptoms and signs in DFNA9 (COCH) and sometimes in DFNA11 (MYO7A). 12324385 2002
Entrez Id: 1729
Gene Symbol: DIAPH1
DIAPH1 		0.120 Biomarker disease HPO
Entrez Id: 10522
Gene Symbol: DEAF1
DEAF1 		0.100 GeneticVariation disease CLINVAR Functional analysis of novel DEAF1 variants identified through clinical exome sequencing expands DEAF1-associated neurodevelopmental disorder (DAND) phenotype. 28940898 2017
Entrez Id: 7466
Gene Symbol: WFS1
WFS1 		0.050 GeneticVariation disease BEFREE Exome sequencing identifies a novel missense mutation of WFS1 as the cause of non-syndromic low-frequency hearing loss in a Chinese family. 28802351 2017
Entrez Id: 7466
Gene Symbol: WFS1
WFS1 		0.050 GeneticVariation disease BEFREE Two individuals who had heterozygosity of GJB2 mutations and heterozygosity of WFS1 mutations showed low-frequency hearing loss. 22498363 2012
Entrez Id: 7466
Gene Symbol: WFS1
WFS1 		0.050 GeneticVariation disease BEFREE Mutations in the WFS1 gene are a frequent cause of autosomal dominant nonsyndromic low-frequency hearing loss in Japanese. 17492394 2007
Entrez Id: 7466
Gene Symbol: WFS1
WFS1 		0.050 GeneticVariation disease BEFREE Studies in low-frequency hearing loss families showed that mutations in WFS1 were responsible for the phenotype. 12650912 2003
Entrez Id: 7466
Gene Symbol: WFS1
WFS1 		0.050 GeneticVariation disease BEFREE Unusual phenotypes in autosomal dominant forms of deafness, include low frequency hearing loss in DFNA1 (HDIA1) and DFNA6/14/38 (WFS1), mid-frequency hearing loss in DFNA8/12 (TECTA), DFNA13 (COL11A2) and vestibular symptoms and signs in DFNA9 (COCH) and sometimes in DFNA11 (MYO7A). 12324385 2002
Entrez Id: 4647
Gene Symbol: MYO7A
MYO7A 		0.020 GeneticVariation disease BEFREE Here, we present the clinical, genetic and molecular characteristics of two large Chinese DFNA11 families with either high- or low-frequency hearing loss. 21150918 2011
Entrez Id: 4647
Gene Symbol: MYO7A
MYO7A 		0.020 GeneticVariation disease BEFREE Unusual phenotypes in autosomal dominant forms of deafness, include low frequency hearing loss in DFNA1 (HDIA1) and DFNA6/14/38 (WFS1), mid-frequency hearing loss in DFNA8/12 (TECTA), DFNA13 (COL11A2) and vestibular symptoms and signs in DFNA9 (COCH) and sometimes in DFNA11 (MYO7A). 12324385 2002
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A 		0.010 AlteredExpression disease BEFREE HA>CI participants with mild low-frequency hearing loss showed the highest levels of bimodal improvement over the best unimodal condition on CNC words. 30067559 2019
Entrez Id: 1257
Gene Symbol: CNC2
CNC2 		0.010 AlteredExpression disease BEFREE HA>CI participants with mild low-frequency hearing loss showed the highest levels of bimodal improvement over the best unimodal condition on CNC words. 30067559 2019
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1 		0.010 AlteredExpression disease BEFREE HA>CI participants with mild low-frequency hearing loss showed the highest levels of bimodal improvement over the best unimodal condition on CNC words. 30067559 2019
Entrez Id: 5172
Gene Symbol: SLC26A4
SLC26A4 		0.010 GeneticVariation disease BEFREE Vestibular function is associated with residual low-frequency hearing loss in patients with bi-allelic mutations in the SLC26A4 gene. 26900070 2016
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB 		0.010 GeneticVariation disease BEFREE A novel missense variant in PRKCB segregates low-frequency hearing loss in an autosomal dominant family with Meniere's disease. 27329761 2016
Entrez Id: 2706
Gene Symbol: GJB2
GJB2 		0.010 GeneticVariation disease BEFREE Two individuals who had heterozygosity of GJB2 mutations and heterozygosity of WFS1 mutations showed low-frequency hearing loss. 22498363 2012
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.010 Biomarker disease BEFREE In addition to Wolfram syndrome gene 1 (DFNA6/14/38) and diaphanous (DFNA1) there is evidence for a third gene involved in low-frequency hearing loss located at DFNA15. 15490091 2004
Entrez Id: 448962
Gene Symbol: DFNA54
DFNA54 		0.010 GeneticVariation disease BEFREE DFNA54, a third locus for low-frequency hearing loss. 15490091 2004
Entrez Id: 1690
Gene Symbol: COCH
COCH 		0.010 GeneticVariation disease BEFREE Unusual phenotypes in autosomal dominant forms of deafness, include low frequency hearing loss in DFNA1 (HDIA1) and DFNA6/14/38 (WFS1), mid-frequency hearing loss in DFNA8/12 (TECTA), DFNA13 (COL11A2) and vestibular symptoms and signs in DFNA9 (COCH) and sometimes in DFNA11 (MYO7A). 12324385 2002
Entrez Id: 1302
Gene Symbol: COL11A2
COL11A2 		0.010 GeneticVariation disease BEFREE Unusual phenotypes in autosomal dominant forms of deafness, include low frequency hearing loss in DFNA1 (HDIA1) and DFNA6/14/38 (WFS1), mid-frequency hearing loss in DFNA8/12 (TECTA), DFNA13 (COL11A2) and vestibular symptoms and signs in DFNA9 (COCH) and sometimes in DFNA11 (MYO7A). 12324385 2002
Entrez Id: 7007
Gene Symbol: TECTA
TECTA 		0.010 GeneticVariation disease BEFREE Unusual phenotypes in autosomal dominant forms of deafness, include low frequency hearing loss in DFNA1 (HDIA1) and DFNA6/14/38 (WFS1), mid-frequency hearing loss in DFNA8/12 (TECTA), DFNA13 (COL11A2) and vestibular symptoms and signs in DFNA9 (COCH) and sometimes in DFNA11 (MYO7A). 12324385 2002