Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3972
Gene Symbol: LHB
LHB 		0.700 GeneticVariation disease UNIPROT Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone. 1727547 1992
Entrez Id: 3972
Gene Symbol: LHB
LHB 		0.700 Biomarker disease CTD_human
Entrez Id: 3972
Gene Symbol: LHB
LHB 		0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 3972
Gene Symbol: LHB
LHB 		0.700 CausalMutation disease CLINVAR
Entrez Id: 3972
Gene Symbol: LHB
LHB 		0.700 GermlineCausalMutation disease ORPHANET
Entrez Id: 2798
Gene Symbol: GNRHR
GNRHR 		0.210 Biomarker disease MGD A novel mouse model of hypogonadotrophic hypogonadism: N-ethyl-N-nitrosourea-induced gonadotropin-releasing hormone receptor gene mutation. 15625238 2005
Entrez Id: 2798
Gene Symbol: GNRHR
GNRHR 		0.210 GeneticVariation disease BEFREE Herein, we describe a 26-yr-old male with a mild phenotypic form of IHH, the fertile eunuch syndrome (IHH in the presence of normal testicular size and some degree of spermatogenesis), associated with a homozygous mutation (Gln106Arg) in the GnRH-R. 11397842 2001
Entrez Id: 6870
Gene Symbol: TACR3
TACR3 		0.200 Biomarker disease MGD Uncovering novel reproductive defects in neurokinin B receptor null mice: closing the gap between mice and men. 22253416 2012
Entrez Id: 84634
Gene Symbol: KISS1R
KISS1R 		0.200 Biomarker disease MGD Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice. 22067321 2012
Entrez Id: 2691
Gene Symbol: GHRH
GHRH 		0.200 Biomarker disease MGD GH, but not GHRH, plays a role in the development of experimental autoimmune encephalomyelitis. 21846799 2011
Entrez Id: 2796
Gene Symbol: GNRH1
GNRH1 		0.200 Biomarker disease MGD Sertoli cell androgen receptor DNA binding domain is essential for the completion of spermatogenesis. 19574395 2009
Entrez Id: 6870
Gene Symbol: TACR3
TACR3 		0.200 Biomarker disease MGD Disruption of the neurokinin-3 receptor (NK3) in mice leads to cognitive deficits. 17558564 2007
Entrez Id: 84634
Gene Symbol: KISS1R
KISS1R 		0.200 Biomarker disease MGD Kiss1-/- mice exhibit more variable hypogonadism than Gpr54-/- mice. 17595229 2007
Entrez Id: 3814
Gene Symbol: KISS1
KISS1 		0.200 Biomarker disease MGD Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. 17563351 2007
Entrez Id: 3814
Gene Symbol: KISS1
KISS1 		0.200 Biomarker disease MGD Kiss1-/- mice exhibit more variable hypogonadism than Gpr54-/- mice. 17595229 2007
Entrez Id: 84634
Gene Symbol: KISS1R
KISS1R 		0.200 Biomarker disease MGD Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. 15665093 2005
Entrez Id: 2691
Gene Symbol: GHRH
GHRH 		0.200 Biomarker disease MGD A mouse with targeted ablation of the growth hormone-releasing hormone gene: a new model of isolated growth hormone deficiency. 15155578 2004
Entrez Id: 1444
Gene Symbol: CSHL1
CSHL1 		0.200 Biomarker disease MGD A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity. 14726450 2004
Entrez Id: 84634
Gene Symbol: KISS1R
KISS1R 		0.200 Biomarker disease MGD The GPR54 gene as a regulator of puberty. 14573733 2003
Entrez Id: 84634
Gene Symbol: KISS1R
KISS1R 		0.200 Biomarker disease MGD The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system. 14652023 2003
Entrez Id: 2796
Gene Symbol: GNRH1
GNRH1 		0.200 Biomarker disease MGD Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism. 198666 1977
Entrez Id: 2516
Gene Symbol: NR5A1
NR5A1 		0.200 Biomarker disease MGD