Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		0.410 Biomarker phenotype BEFREE NICTH is characterised by recurrent fasting hypoglycaemia and is associated with the secretion of incompletely processed precursors of IGF-II ('big'-IGF-II) by the tumour. 18045950 2007
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		0.410 Biomarker phenotype CTD_human Synthesis and secretion of insulin-like growth factor II by a leiomyosarcoma with associated hypoglycemia. 3185662 1988
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		0.410 Biomarker phenotype HPO
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A 		0.400 Biomarker phenotype CTD_human Preserved insulin response to tolbutamide in hepatocyte nuclear factor-1alpha mutation carriers. 15787664 2005
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A 		0.400 Biomarker phenotype HPO
Entrez Id: 3630
Gene Symbol: INS
INS 		0.310 Biomarker phenotype CTD_human Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance. 22940631 2013
Entrez Id: 3630
Gene Symbol: INS
INS 		0.310 Biomarker phenotype CTD_human Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. 20620209 2010
Entrez Id: 3630
Gene Symbol: INS
INS 		0.310 Biomarker phenotype CTD_human Effect of hypotension and hyperosmolality on vasopressin and ACTH responses to hypoglycemia in conscious dogs. 1324617 1992
Entrez Id: 3630
Gene Symbol: INS
INS 		0.310 Biomarker phenotype CTD_human ACTH and vasopressin responses to insulin-induced hypoglycemia in intact and neurohypophysectomized conscious dogs. 1646414 1991
Entrez Id: 3630
Gene Symbol: INS
INS 		0.310 Biomarker phenotype CTD_human Hypothalamic modulation of growth hormone secretion in the rhesus monkey: evidence from intracerebroventricular infusions of glucose, free fatty acid, and ketone bodies. 1890151 1991
Entrez Id: 3630
Gene Symbol: INS
INS 		0.310 Biomarker phenotype CTD_human Psychoneuroendocrine effects of methadone maintenance. 2554359 1989
Entrez Id: 3630
Gene Symbol: INS
INS 		0.310 Biomarker phenotype BEFREE This assay will be useful for confirming the diagnosis of insulin-secreting tumor in patients suspected of recurrent fasting hypoglycemia and in physiologic studies of proinsulin secretion. 3023795 1986
Entrez Id: 3630
Gene Symbol: INS
INS 		0.310 Biomarker phenotype CTD_human Modification by propranolol of cardiovascular effects of induced hypoglycaemia. 48835 1975
Entrez Id: 2936
Gene Symbol: GSR
GSR 		0.300 Biomarker phenotype CTD_human Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. 20620209 2010
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Biomarker phenotype CTD_human Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. 20620209 2010
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		0.300 Biomarker phenotype CTD_human Art, alpha-1-antitrypsin polymorphisms and intense creative energy: blessing or curse? 17659342 2007
Entrez Id: 5465
Gene Symbol: PPARA
PPARA 		0.300 Biomarker phenotype CTD_human Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain. 16777972 2006
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C 		0.300 Biomarker phenotype CTD_human Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. 15454078 2004
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker phenotype CTD_human Dexamethasone attenuates hypoglycemia in ten day old rats treated with TNF alpha. 8774068 1996
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.300 Biomarker phenotype CTD_human A phase I trial of recombinant human interleukin-1 beta alone and in combination with myelosuppressive doses of 5-fluorouracil in patients with gastrointestinal cancer. 1884014 1991
Entrez Id: 2998
Gene Symbol: GYS2
GYS2 		0.110 GeneticVariation phenotype BEFREE Biochemical evaluation as well as direct sequencing of exons and exon-intron boundary regions of the GYS2 gene were performed in a patient presenting fasting hypoglycemia and postprandial hyperglycemia and her parents. 20051115 2010
Entrez Id: 2998
Gene Symbol: GYS2
GYS2 		0.110 Biomarker phenotype HPO
Entrez Id: 3643
Gene Symbol: INSR
INSR 		0.100 Biomarker phenotype HPO
Entrez Id: 9095
Gene Symbol: TBX19
TBX19 		0.100 Biomarker phenotype HPO
Entrez Id: 2203
Gene Symbol: FBP1
FBP1 		0.100 Biomarker phenotype HPO