Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8328
Gene Symbol: GFI1B
GFI1B 		0.010 GeneticVariation disease BEFREE Macrothrombocytopenia associated with a rare GFI1B missense variant confounding the presentation of immune thrombocytopenia. 31207059 2019
Entrez Id: 3589
Gene Symbol: IL11
IL11 		0.010 Biomarker disease BEFREE Platelet and peripheral white blood cell counts at diagnosis predict the response of adult immune thrombocytopenia to recombinant human interleukin-11: A retrospective, single-center, case-control study. 31008943 2019
Entrez Id: 6850
Gene Symbol: SYK
SYK 		0.010 Biomarker disease BEFREE The pharmacology, pharmacokinetics, efficacy, safety, dosing and administration, and place in therapy of fostamatinib, a novel spleen tyrosine kinase inhibitor for the treatment of adult immune thrombocytopenia that has had an insufficient response to a previous treatment are summarized. 30951590 2019
Entrez Id: 2814
Gene Symbol: GP5
GP5 		0.010 Biomarker disease BEFREE Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia. 30923095 2019
Entrez Id: 7293
Gene Symbol: TNFRSF4
TNFRSF4 		0.010 Biomarker disease BEFREE Increased Expressions of OX40 and OX40 Ligand in Patients with Primary Immune Thrombocytopenia. 30944836 2019
Entrez Id: 27178
Gene Symbol: IL37
IL37 		0.010 AlteredExpression disease BEFREE Plasma levels and expression of interleukin-37 in patients with immune thrombocytopenia. 31572521 2019
Entrez Id: 7189
Gene Symbol: TRAF6
TRAF6 		0.010 Biomarker disease BEFREE A biomarker and therapeutical target in immune thrombocytopenia: TNF receptor-associated factor 6. 30556735 2019
Entrez Id: 3111
Gene Symbol: HLA-DOA
HLA-DOA 		0.010 GeneticVariation disease BEFREE Association of cytotoxic T-lymphocyte antigen 4 gene with immune thrombocytopenia in Chinese Han children. 30319055 2019
Entrez Id: 64170
Gene Symbol: CARD9
CARD9 		0.010 GeneticVariation disease BEFREE A CARD9 single-nucleotide polymorphism rs4077515 is associated with reduced susceptibility to and severity of primary immune thrombocytopenia. 31595308 2019
Entrez Id: 1235
Gene Symbol: CCR6
CCR6 		0.010 Biomarker disease BEFREE CCR6 defines a subset of activated memory T cells of Th17 potential in immune thrombocytopenia. 30403287 2019
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.010 GeneticVariation disease BEFREE JAK2 V617F-positive essential thrombocythemia with subsequent development of immune thrombocytopenia: A case report. 31689837 2019
Entrez Id: 3662
Gene Symbol: IRF4
IRF4 		0.010 Biomarker disease BEFREE Transcription Factor IRF4 Dysfunction Affects the Immunosuppressive Function of Treg Cells in Patients with Primary Immune Thrombocytopenia. 31380412 2019
Entrez Id: 6403
Gene Symbol: SELP
SELP 		0.010 Biomarker disease BEFREE Effect of thrombopoietin receptor agonists on markers of coagulation and P-selectin in patients with immune thrombocytopenia. 29215956 2019
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1 		0.010 Biomarker disease BEFREE Higher CD56+ or CD2+ lymphocyte percentage predicts poor steroid response in patients with immune thrombocytopenia. 31669825 2019
Entrez Id: 7292
Gene Symbol: TNFSF4
TNFSF4 		0.010 Biomarker disease BEFREE Increased Expressions of OX40 and OX40 Ligand in Patients with Primary Immune Thrombocytopenia. 30944836 2019
Entrez Id: 28477
Gene Symbol: IGHJ4
IGHJ4 		0.010 Biomarker disease BEFREE High-throughput sequencing of IgG B-cell receptors reveals frequent usage of the rearranged IGHV4-28/IGHJ4 gene in primary immune thrombocytopenia. 31201346 2019
Entrez Id: 3603
Gene Symbol: IL16
IL16 		0.010 Biomarker disease BEFREE High-Dose Dexamethasone Alters the Increase in Interleukin-16 Level in Adult Immune Thrombocytopenia. 30936868 2019
Entrez Id: 9002
Gene Symbol: F2RL3
F2RL3 		0.010 Biomarker disease BEFREE A reduction in response to GPVI and CLEC-2, but not protease-activated receptor 4 (PAR-4) peptide, was also observed in adult mouse platelets following immune thrombocytopenia, whereas receptor expression was not impaired. 29695020 2018
Entrez Id: 102
Gene Symbol: ADAM10
ADAM10 		0.010 AlteredExpression disease BEFREE Increased ADAM10 expression in patients with immune thrombocytopenia. 29223855 2018
Entrez Id: 51266
Gene Symbol: CLEC1B
CLEC1B 		0.010 Biomarker disease BEFREE Significant Hypo-Responsiveness to GPVI and CLEC-2 Agonists in Pre-Term and Full-Term Neonatal Platelets and following Immune Thrombocytopenia. 29695020 2018
Entrez Id: 350
Gene Symbol: APOH
APOH 		0.010 AlteredExpression disease BEFREE Diminished expression of β2-GPI is associated with a reduced ability to mitigate complement activation in anti-GPIIb/IIIa-mediated immune thrombocytopenia. 29350259 2018
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1 		0.010 GeneticVariation disease BEFREE PDCD1 and CTLA4 polymorphisms affect the susceptibility to, and clinical features of, chronic immune thrombocytopenia. 29359792 2018
Entrez Id: 51206
Gene Symbol: GP6
GP6 		0.010 Biomarker disease BEFREE Significant Hypo-Responsiveness to GPVI and CLEC-2 Agonists in Pre-Term and Full-Term Neonatal Platelets and following Immune Thrombocytopenia. 29695020 2018
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3 		0.010 Biomarker disease BEFREE Mesenchymal stem cell deficiency influences megakaryocytopoiesis through the TNFAIP3/NF-κB/SMAD pathway in patients with immune thrombocytopenia. 29327472 2018
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.010 GeneticVariation disease BEFREE PDCD1 and CTLA4 polymorphisms affect the susceptibility to, and clinical features of, chronic immune thrombocytopenia. 29359792 2018