Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4352
Gene Symbol: MPL
MPL 		0.100 Biomarker disease BEFREE Immune thrombocytopenia is associated with persistently deranged fibrosis-related seromarker profiles but low bone marrow fibrosis grades: A 2-year observational study on thrombopoietin receptor agonist treatment. 29293383 2019
Entrez Id: 961
Gene Symbol: CD47
CD47 		0.020 AlteredExpression disease BEFREE CD47 is expressed at normal levels in patients with autoimmune haemolytic anaemia and/or immune thrombocytopenia. 17163870 2006
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.040 GeneticVariation disease BEFREE Interleukin-10 gene polymorphism reflects the severity of chronic immune thrombocytopenia in Japanese patients. 21463487 2011
Entrez Id: 112744
Gene Symbol: IL17F
IL17F 		0.040 GeneticVariation disease BEFREE Interleukin-17F gene polymorphism in patients with chronic immune thrombocytopenia. 21615796 2011
Entrez Id: 971
Gene Symbol: CD72
CD72 		0.020 AlteredExpression disease BEFREE CD72 gene expression in immune thrombocytopenia. 22111667 2012
Entrez Id: 648
Gene Symbol: BMI1
BMI1 		0.010 Biomarker disease BEFREE Bmi-1 regulates autoreactive CD4+ T cell survival in immune thrombocytopenia patients. 22293918 2012
Entrez Id: 100532731
Gene Symbol: COMMD3-BMI1
COMMD3-BMI1 		0.010 Biomarker disease BEFREE Bmi-1 regulates autoreactive CD4+ T cell survival in immune thrombocytopenia patients. 22293918 2012
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22 		0.010 GeneticVariation disease BEFREE PTPN22 -1123G > C polymorphism is associated with susceptibility to primary immune thrombocytopenia in Chinese population. 23098231 2013
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A 		0.010 GeneticVariation disease BEFREE FcγRIIa and FcγRIIIa polymorphisms in childhood primary immune thrombocytopenia: implications for disease pathogenesis and outcome. 23249566 2013
Entrez Id: 6007
Gene Symbol: RHD
RHD 		0.010 Biomarker disease BEFREE RHD zygosity predicts degree of platelet response to anti-D immune globulin treatment in children with immune thrombocytopenia. 23712954 2013
Entrez Id: 53342
Gene Symbol: IL17D
IL17D 		0.030 GeneticVariation disease BEFREE Interleukin-27 rs153109 polymorphism and the risk for immune thrombocytopenia. 23937109 2013
Entrez Id: 246778
Gene Symbol: IL27
IL27 		0.030 GeneticVariation disease BEFREE Interleukin-27 rs153109 polymorphism and the risk for immune thrombocytopenia. 23937109 2013
Entrez Id: 3606
Gene Symbol: IL18
IL18 		0.030 GeneticVariation disease BEFREE Interleukin-18 gene promoter--607 A/C polymorphism and the risk of immune thrombocytopenia. 24897237 2014
Entrez Id: 942
Gene Symbol: CD86
CD86 		0.010 GeneticVariation disease BEFREE CD86 +1057G/A polymorphism and risk of chronic immune thrombocytopenia. 24897540 2014
Entrez Id: 10673
Gene Symbol: TNFSF13B
TNFSF13B 		0.020 Biomarker disease BEFREE B-cell-activating factor, a proliferation inducing ligand and co-stimulatory molecules in the pathogenesis of immune thrombocytopenia in childhood. 24911453 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.060 GeneticVariation disease BEFREE TNF-α promoter single nucleotide polymorphisms and haplotypes associate with susceptibility of immune thrombocytopenia in Chinese adults. 25158149 2014
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3 		0.010 PosttranslationalModification disease BEFREE Foxp3 methylation status in children with primary immune thrombocytopenia. 25305033 2014
Entrez Id: 6772
Gene Symbol: STAT1
STAT1 		0.010 GeneticVariation disease BEFREE STAT1 single nucleotide polymorphisms and susceptibility to immune thrombocytopenia. 25707685 2015
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12 		0.010 GeneticVariation disease BEFREE Stromal cell-derived factor-1 rs2297630 polymorphism associated with platelet production and treatment response in Chinese patients with chronic immune thrombocytopenia. 26587874 2016
Entrez Id: 149233
Gene Symbol: IL23R
IL23R 		0.020 GeneticVariation disease BEFREE Interleukin-23 receptor rs1884444 single nucleotide polymorphism was studied in 50 patients with primary immune thrombocytopenia and 100 healthy age and sex-matched controls by polymerase chain reaction amplification of the target gene followed by allele-specific restriction enzyme digestion. 26859125 2016
Entrez Id: 4352
Gene Symbol: MPL
MPL 		0.100 Biomarker disease BEFREE Thrombopoietin-receptor-agonists (TPO-RAs) increase platelet production in Immune Thrombocytopenia (ITP) by stimulating Mpl. 27819522 2017
Entrez Id: 4352
Gene Symbol: MPL
MPL 		0.100 Biomarker disease BEFREE Thrombopoietin receptor agonists in patients with persistent or chronic immune thrombocytopenia. 29243329 2018
Entrez Id: 7066
Gene Symbol: THPO
THPO 		0.100 AlteredExpression disease BEFREE Thrombopoietin and its receptor expression in pediatric patients with chronic immune thrombocytopenia. 29313460 2018
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1 		0.010 GeneticVariation disease BEFREE PDCD1 and CTLA4 polymorphisms affect the susceptibility to, and clinical features of, chronic immune thrombocytopenia. 29359792 2018
Entrez Id: 2896
Gene Symbol: GRN
GRN 		0.010 Biomarker disease BEFREE Progranulin facilitates the increase of platelet count in immune thrombocytopenia. 29475178 2018