Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4
0.010 Biomarker phenotype BEFREE Simulated crisis management sessions were initiated during which two trained raters evaluated the performance of postgraduate first-, second- and third-year (PGY-1, PGY-2 and PGY-3) anaesthesia residents. 28673217 2017
Entrez Id: 28
Gene Symbol: ABO
ABO
0.010 Biomarker phenotype BEFREE Standard laboratory coagulation tests and ABO blood typing are still routinely prescribed before surgery and anaesthesia despite current guidelines. 29136093 2017
Entrez Id: 43
Gene Symbol: ACHE
ACHE
0.010 Biomarker phenotype BEFREE Also, the high-affinity choline uptake (HACU) in hippocampal synaptosomes from awake hAChE-Tg mice was accelerated but was reduced by halothane anaesthesia. 11299326 2001
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1
0.010 AlteredExpression phenotype BEFREE Using PACAP receptor knockout mice, and pharmacological agents in Sprague Dawley rats, we measured blood pressure, heart rate, pH, PaCO<sub>2</sub>, and splanchnic sympathetic nerve activity, under anaesthesia, to demonstrate that the sympathetic response to AIH is mediated via the PAC1 receptor, in a cAMP-dependent manner. 31496933 2019
Entrez Id: 10974
Gene Symbol: ADIRF
ADIRF
0.010 AlteredExpression phenotype BEFREE In March 2018, a group of 79 high-level global SOA stakeholders from 25 countries in the WHO AFRO and EMRO regions gathered in Dubai to provide technical and strategic guidance for the creation and expansion of NSOAPs. 30298283 2019
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
0.020 GeneticVariation phenotype BEFREE β2-Adrenoceptor gene variants affect vasopressor requirements in patients after thoracic epidural anaesthesia. 24366725 2014
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
0.020 GeneticVariation phenotype BEFREE In conclusion, our results demonstrate that haplotype variations of the the ADRB2 modulate the haemodynamic response following spinal anaesthesia for caesarean delivery. 22881137 2012
Entrez Id: 27161
Gene Symbol: AGO2
AGO2
0.010 AlteredExpression phenotype BEFREE To measure the plasma concentrations of three endogenous opioid peptides and the levels of preproenkephalin (PPE) and preprodynorphin (PPD) mRNA in peripheral blood lymphocytes of patients during scheduled surgery performed under intravenous general anaesthesia combined with an epidural block. 24743873 2014
Entrez Id: 181
Gene Symbol: AGRP
AGRP
0.010 Biomarker phenotype BEFREE Ninety-nine patients who met the inclusion criteria and presented with carious lesions were randomly allocated to receive either ART or conventional restorations (anaesthesia, rotary instruments and resin-modified glass ionomer). 30862556 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
0.020 Biomarker phenotype BEFREE Albumin solutions were increasingly issued to anaesthesia departments (63%; P = 0.005) and was rarely issued to general surgery and orthopaedic departments. 28374467 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
0.020 Biomarker phenotype BEFREE Although the plasma albumin concentrations (35.46 ± 4.13 vs 44.10 ± 1.12 mmol/L, respectively, P < .05) and dosage of propofol were significantly lower in the Renal-failure Group than in the Control Group (81.68 ± 18.08 vs 63.07 ± 13.45 μg/kg/min, respectively, P < .05), there were no differences in the context-sensitive half-life and the revival time of anaesthesia between the 2 groups. 29247451 2018
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 GeneticVariation phenotype BEFREE Two-hundred and three ASA I-II patients, <18 years of age (mean: 5.3 ± 2.4 years) were included in the prospective observational study whose comprehensive dental treatment was performed under general anaesthesia. 28108831 2018
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 GeneticVariation phenotype BEFREE Children (1-16 yr old, ASA I or II) undergoing elective procedures with general anaesthesia requiring tracheal intubation were randomised for clear fluid intake until premedication with midazolam (liberal) or 2 h fluid fasting (standard).Actual fasting times were recorded. 30115263 2018
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 Biomarker phenotype BEFREE We evaluated ASA physical status III and IV patients who had non-cardiac surgery with general anaesthesia at the Cleveland Clinic. 29452806 2018
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 Biomarker phenotype BEFREE In a prospective, open label, observational study, 292 ASA physical status classification 1 and 2 patients at low risk of pulmonary aspiration undergoing upper gastrointestinal endoscopy received i.v. propofol anaesthesia and standardized insertion of the LMA<sup>®</sup>Gastro<sup>TM</sup> Airway. 29406183 2018
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 Biomarker phenotype BEFREE Eighty ASA physical status 1-2 patients scheduled for shoulder arthroscopy under general anaesthesia with ultrasound-guided interscalene brachial plexus block were randomly allocated to receive saline (control), dexamethasone 1 mg, 2 mg, 3 mg and 4 mg, together with 20 ml ropivacaine 0.5%. 30973188 2019
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 Biomarker phenotype BEFREE We studied 74 paediatric patients aged 0-24 months of ASA physical status 1-3 who were scheduled for elective surgery under general anaesthesia. 30987765 2019
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 Biomarker phenotype BEFREE Age, sex, height, weight, ASA physical status, days in hospital before anaesthesia, number of anaesthetics per child, indications for anaesthesia, methods of anaesthesia, airway management and complications were all recorded. 29672828 2018
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 Biomarker phenotype BEFREE Longer duration of anaesthesia, inhalational anaesthesia and ASA ≥3 were significantly associated to this. 31241184 2019
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 GeneticVariation phenotype BEFREE Thirty-one adult ASA I-III patients undergoing long-duration (>3 hours) sevoflurane anaesthesia for major head and neck surgery were included and randomized to IHV-treatment (n = 16) or control (n = 15). 29671866 2018
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 Biomarker phenotype BEFREE A logistic regression analysis with risk factors (age, ASA physical status, emergency) was used to evaluate the impact of implementation of the specialised paediatric anaesthesia team. 30048261 2019
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 Biomarker phenotype BEFREE Female cats (American Society of Anesthesiologists [ASA] grade I) undergoing elective surgery by laparotomy under general anaesthesia (acepromazine 0.05 mg/kg SC; morphine 0.2 mg/kg IV; propofol IV titrated, isoflurane 2% in 100% oxygen) were randomised in two groups. 28121211 2017
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 Biomarker phenotype BEFREE Children with an ASA physical state classification of I or II, aged from 4 to 16 years and scheduled for elective circumcision or inguinal hernia repair under combined general and caudal anaesthesia were included. 28685824 2017
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.100 GeneticVariation phenotype BEFREE Twenty-two adult ASA I to III patients scheduled to undergo elective surgical procedures under general anaesthesia requiring administration of a neuromuscular blocking agent were included. 30446866 2019
Entrez Id: 9048
Gene Symbol: ARTN
ARTN
0.010 Biomarker phenotype BEFREE Ninety-nine patients who met the inclusion criteria and presented with carious lesions were randomly allocated to receive either ART or conventional restorations (anaesthesia, rotary instruments and resin-modified glass ionomer). 30862556 2019