Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE CD44-associated radioresistance of glioblastoma in irradiated brain areas with optimal tumor coverage. 31746135 2020
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE These results indicate that galangin is a potential novel drug for glioblastoma treatment due to its ability to suppress of CD44, EMT and angiogenesis. 31528214 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE Interestingly, SWAP-70 expression was positively correlated with the expression of the standard form of CD44 (CD44s) in GB tissues. 31832018 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE Here we show that soluble CD44 secreted from glioblastoma cells induces neuronal degeneration through the activation of tau pathology in the brain. 29622771 2018
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE In summary, novel CD44 targeted polymeric based nanocarriers appear to be proficient in mediating site-specific delivery of quercetin via CD44 receptor in glioblastoma cells. 29030990 2018
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease BEFREE Targeting Glioblastoma Cells Expressing CD44 with Liposomes Encapsulating Doxorubicin and Displaying Chlorotoxin-IgG Fc Fusion Protein. 29495404 2018
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease BEFREE Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma. 30210550 2018
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease BEFREE Epithelial membrane protein 3 regulates TGF-β signaling activation in CD44-high glioblastoma. 27527869 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease BEFREE The results suggest that upregulation of NG2/CSPG4 rather than changes in CD44 or Ki-67 expression is associated with low overall survival in glioblastoma multiforme patients, supporting NG2/CSPG4 as a potential prognostic marker in glioblastoma. 28945172 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease BEFREE Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity. 28241049 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease BEFREE Overexpression of endogenous CD44 (cancer stem cell marker) promotes phosphorylation/inactivation of NF2, and upregulates YAP1 expression and leads to cancer cell resistance in glioblastoma. 25750037 2015
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE Finally, we identify a BT-MSC population in human glioblastoma that is CD44+CD9+CD166+ both in freshly isolated and culture-expanded cells. 24302539 2014
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE Regulatory factor X1 bound to the CD44 gene in glioblastoma cells. 24526308 2014
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease BEFREE TGM2 was highly expressed in CD44-high glioblastoma tissues and tumor-derived glioma-initiating cell lines. 23877317 2013
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells. 22024282 2012
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 AlteredExpression disease BEFREE CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma. 20197461 2010
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE TGF-β Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma. 21156287 2010
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE CD44 has been proposed as an invasion marker for glioblastoma. 9436970 1997