Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1021
Gene Symbol: CDK6
CDK6 		0.310 AlteredExpression disease BEFREE Here, we show that microRNA-200a decreases CDK6 expression and thus reduces the response of CDK4/6 inhibitor in highly proliferative metastatic melanoma. 28526299 2017
Entrez Id: 5587
Gene Symbol: PRKD1
PRKD1 		0.310 Biomarker disease BEFREE In conclusion, our study suggests, for the first time, that while cPKCs don't embody a pertinent therapeutic target, inhibition of PKD1 represents a novel attractive approach for the treatment of metastatic melanoma. 28056869 2017
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.310 Biomarker disease BEFREE By somatically inactivating Lkb1 with K-Ras activation (±p53 loss) in murine melanocytes, we observed variably pigmented and highly metastatic melanoma with 100% penetrance. 22698401 2012
Entrez Id: 4293
Gene Symbol: MAP3K9
MAP3K9 		0.310 GeneticVariation disease BEFREE Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. 22197930 2011
Entrez Id: 2043
Gene Symbol: EPHA4
EPHA4 		0.310 Biomarker disease BEFREE Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma. 9185712 1997
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.310 GeneticVariation disease UNIPROT
Entrez Id: 5587
Gene Symbol: PRKD1
PRKD1 		0.310 GeneticVariation disease UNIPROT
Entrez Id: 1021
Gene Symbol: CDK6
CDK6 		0.310 GeneticVariation disease UNIPROT
Entrez Id: 4293
Gene Symbol: MAP3K9
MAP3K9 		0.310 GeneticVariation disease UNIPROT
Entrez Id: 2043
Gene Symbol: EPHA4
EPHA4 		0.310 GeneticVariation disease UNIPROT
Entrez Id: 22983
Gene Symbol: MAST1
MAST1 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 3000
Gene Symbol: GUCY2D
GUCY2D 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 11184
Gene Symbol: MAP4K1
MAP4K1 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 84446
Gene Symbol: BRSK1
BRSK1 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 7273
Gene Symbol: TTN
TTN 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 23178
Gene Symbol: PASK
PASK 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 389840
Gene Symbol: MAP3K15
MAP3K15 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 202374
Gene Symbol: STK32A
STK32A 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 57144
Gene Symbol: PAK5
PAK5 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 4919
Gene Symbol: ROR1
ROR1 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 2046
Gene Symbol: EPHA8
EPHA8 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 9475
Gene Symbol: ROCK2
ROCK2 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 9149
Gene Symbol: DYRK1B
DYRK1B 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 658
Gene Symbol: BMPR1B
BMPR1B 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 150094
Gene Symbol: SIK1
SIK1 		0.300 GeneticVariation disease UNIPROT