Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.120 Biomarker disease BEFREE LPAR1 regulates the development of intratumoral heterogeneity in ovarian serous cystadenocarcinoma by activating the PI3K/AKT signaling pathway. 31384176 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.120 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.120 AlteredExpression disease BEFREE Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma. 18574502 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.110 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.110 GeneticVariation disease BEFREE Expression of mutant p53 in 19 patients with stage III moderately differentiated serous cystadenocarcinoma of the ovary, who all had optimal primary cytoreductive surgery and six cycles of cisplatin and cyclophosphamide was analyzed to determine its prognostic significance. 10472362 1999
Entrez Id: 5518
Gene Symbol: PPP2R1A
PPP2R1A 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 567
Gene Symbol: B2M
B2M 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		0.020 Biomarker disease BEFREE To explore the role of lysophosphatidic acid receptor 1 (LPAR1) and its correlation with the PI3K/AKT pathway in the development of intratumoral heterogeneity (ITH) in human ovarian serous cystadenocarcinoma (OSC). 31384176 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.020 Biomarker disease BEFREE Gene correlation analysis revealed that the VEGFA- STAT3-KLF4-CDKN1A signal axis was not only present in head and neck squamous carcinoma (HNSCC) but also two other epithelial-derived carcinomas that highly express VEGFA, including kidney renal clear cell carcinoma (KIRC) and ovarian serous cystadenocarcinoma (OV). 31198634 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.020 Biomarker disease BEFREE LPAR1 regulates the development of intratumoral heterogeneity in ovarian serous cystadenocarcinoma by activating the PI3K/AKT signaling pathway. 31384176 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		0.020 Biomarker disease BEFREE LPAR1 regulates the development of intratumoral heterogeneity in ovarian serous cystadenocarcinoma by activating the PI3K/AKT signaling pathway. 31384176 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		0.020 Biomarker disease BEFREE LPAR1 regulates the development of intratumoral heterogeneity in ovarian serous cystadenocarcinoma by activating the PI3K/AKT signaling pathway. 31384176 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.020 AlteredExpression disease BEFREE Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma. 18574502 2008
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		0.020 AlteredExpression disease BEFREE Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma. 18574502 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.020 AlteredExpression disease BEFREE Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma. 18574502 2008
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		0.020 AlteredExpression disease BEFREE Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma. 18574502 2008
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		0.020 AlteredExpression disease BEFREE Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma. 18574502 2008
Entrez Id: 3491
Gene Symbol: CCN1
CCN1 		0.010 AlteredExpression disease BEFREE In malignant ascites, higher Cyr61 level of ovarian serous cystadenocarcinoma was more closely associated with FIGO stage, initial tumor size > 10 cm and the residual tumor size. 31766991 2019
Entrez Id: 1902
Gene Symbol: LPAR1
LPAR1 		0.010 Biomarker disease BEFREE LPAR1 plays essential roles in the invasion, migration, and proliferation of heterogeneous subsets of OSC cell lines and the development of ITH of OSC, possibly by modulating the activity of the PI3K/AKT signaling pathway. 31384176 2019
Entrez Id: 2949
Gene Symbol: GSTM5
GSTM5 		0.010 Biomarker disease BEFREE In combination with this comprehensive approach, 14 genes, including ABCA10, DCX, LRRC30, ALX4, DKK4, SGCZ, ANKS4B, FHL5, SPRR2F, CHRNG, GABRR1, STMN2, CRHBP, and GSTM5, were shown to serve as candidate biomarkers for predicting the prognosis of patients with OVSC. 31646556 2019