Gene: PIK3CD ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 GeneticVariation disease BEFREE Clinical outcomes and differential effects of PI3K pathway mutation in obese versus non-obese patients with cervical cancer. 29423104 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 GeneticVariation disease BEFREE Here we demonstrate that PTEN destabilization is induced by EGFR- or oncogenic PI3K mutation-mediated AKT activation in cervical cancer. 26183061 2015
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 GeneticVariation disease BEFREE Seventy percent of patients with endometrial cancer and more than 50% of patients with breast, prostate, anal, hepatocellular, colorectal, and cervical cancer exhibited alterations in at least 1 PI3K pathway gene and/or gene product. 27388585 2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Tobacco Exposure Enhances Human Papillomavirus 16 Oncogene Expression via EGFR/PI3K/Akt/c-Jun Signaling Pathway in Cervical Cancer Cells. 30619121 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE let-7i-5p, miR-181a-2-3p and EGF/PI3K/SOX2 axis coordinate to maintain cancer stem cell population in cervical cancer. 29777148 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE CD38 was correlated with dysregulation of the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway in cervical cancer tissues in vitro. 25310288 2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE These results suggest that targeted inhibition of PI3K/AKT may improve response to chemoradiation in cervical cancer. 23899375 2013
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Stathmin is involved in arsenic trioxide-induced apoptosis in human cervical cancer cell lines via PI3K linked signal pathway. 20657188 2010
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE The Potential Value of the PI3K/Akt/mTOR Signaling Pathway for Assessing Prognosis in Cervical Cancer and as a Target for Therapy. 28475243 2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE We suggest that SKA3 overexpression contributes to CC cell growth and migration by promoting cell cycle progression and activating the PI3K-Akt signaling pathway, which may provide potential novel therapeutic targets for CC treatment. 30459531 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE This study aimed to explore the effect of miR-99b-5p (miR-99b) on invasion and migration in cervical cancer through the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mechanistic target of rapamycin (mTOR) signaling pathway. 30480801 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE microRNA-383 suppresses the PI3K-AKT-MTOR signaling pathway to inhibit development of cervical cancer via down-regulating PARP2. 29236322 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE The combined use of BMN673 and BYL719 may serve as a promising therapeutic strategy for patients with cervical cancer exhibiting aberrant PI3K activation. 31545455 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE MicroRNA‑433 inhibits cell growth and induces apoptosis in human cervical cancer through PI3K/AKT signaling by targeting FAK. 30272334 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Taken together, our data suggest that anti-VEGFa treatment in cervical cancer may inhibit both tumor cell growth and invasion through PI3k/Akt/mTor signaling pathway. 25135429 2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Current research elucidated that MFI2 promoted cell proliferation, cell metastasis and inhibited cell apoptosis in cervical cancer by regulating the PI3K/AKT signaling pathway. 31210294 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Knockdown of hnRNP A2/B1 inhibits cell proliferation, invasion and cell cycle triggering apoptosis in cervical cancer via PI3K/AKT signaling pathway. 29328485 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE FOXC1 promotes proliferation and epithelial-mesenchymal transition in cervical carcinoma through the PI3K-AKT signal pathway. 28386355 2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Activation of the PI3K/Akt pathway is associated with incomplete metabolic response in cervical cancer. 22235101 2012
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Inhibition of Phosphatidylinositol 3-kinase (PI3K) Signaling Synergistically Potentiates Antitumor Efficacy of Paclitaxel and Overcomes Paclitaxel-Mediated Resistance in Cervical Cancer. 31295843 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Aberrant activation of the phosphoinositide-3-kinase (PI3K) pathway frequently occurs in solid tumors, including cervical cancer. 28036259 2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE miR-338 modulates proliferation and autophagy by PI3K/AKT/mTOR signaling pathway in cervical cancer. 29898430 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Fibulin-3 promoted cervical cancer cell invasive capabilities by eliciting EMT and activating the PI3K-Akt-mTOR signal transduction pathway. 30006571 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Baicalein inhibits cervical cancer progression via downregulating long noncoding RNA BDLNR and its downstream PI3K/Akt pathway. 29175387 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Western blotting was utilized to validate whether NEAT1 promotes cervical cancer progression through activating PI3K-Akt signaling pathway. 30127216 2018