Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.090 | Biomarker | disease | BEFREE | Our results demonstrate the importance of MLK3 in cervical cancer progression via modulating the Notch-1/autophagy network, and suggest that MLK3 is a promising therapeutic target for cervical cancer. | 31192472 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Notch1 inhibition enhances DNA damage induced by cisplatin in cervical cancer. | 30690027 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | The aim of this study was to investigate the effect of human umbilical vein endothelial cells on epithelial-to-mesenchymal transition of the cervical cancer cell line SiHa by studying the Notch1/lysyl oxidase (LOX)/SNAIL1 pathway. | 31205475 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | The present data proved the over-expression of Notch1/JAGD1 and its association with tumor progression in human cervical cancer, which might be a potential valuable biomarker for cervical cancer and further studies need. | 25842263 | 2015 | ||||
|
0.090 | Biomarker | disease | BEFREE | CD66 and Notch1 were studied in clinical specimens and explants of human cervical cancer, including specimens grown in a pathophysiologically relevant murine model. | 21646470 | 2011 | ||||
|
0.090 | Biomarker | disease | BEFREE | This study has provided evidence to suggest that RhoC is an effector of Notch1 in cervical carcinoma. | 19953094 | 2010 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Knockdown of p63 caused upregulation of Notch1 expression and marked reduction in proliferation and clonogenicity of both normal human keratinocytes and cervical cancer cell lines overexpressing DeltaNp63alpha. | 20442293 | 2010 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells. | 20351093 | 2010 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Features of Notch1 activation as measured by intracellular Notch1, high levels of Jagged1, Hes1 and Cdk9 were paralleled by nuclear translocation of both NF-kappaB p50 and p65 with target gene expression (IkappaB-alpha, Bcl-2, and CyclinD1) in human cervical cancer sections. | 17098279 | 2007 |