| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.010 | GeneticVariation | phenotype | BEFREE | Seventy-five cases were diagnosed based on the American Association of Endodontics's diagnostic criteria and divided into 4 groups: normal pulp with deep caries (NP; n = 13), reversible pulpitis with only cold-evoked pain (CRP; n = 17), reversible pulpitis with both cold/heat-evoked pain (CHRP; n = 24), and symptomatic irreversible pulpitis (SIP; n = 21).Samples were sequenced by 16S rDNA. | 30803537 | 2019 | ||||
|
0.010 | AlteredExpression | phenotype | BEFREE | The expression of EREG and odontoblastic differentiation-related markers was investigated in human dental pulp from teeth with deep caries and healthy teeth. | 31454111 | 2019 | ||||
|
0.010 | GeneticVariation | phenotype | BEFREE | Seventy-five cases were diagnosed based on the American Association of Endodontics's diagnostic criteria and divided into 4 groups: normal pulp with deep caries (NP; n = 13), reversible pulpitis with only cold-evoked pain (CRP; n = 17), reversible pulpitis with both cold/heat-evoked pain (CHRP; n = 24), and symptomatic irreversible pulpitis (SIP; n = 21).Samples were sequenced by 16S rDNA. | 30803537 | 2019 | ||||
|
0.010 | GeneticVariation | phenotype | BEFREE | Therefore, this study comprises a case-control and functional investigation of Tbx21 genetic variations impact on Th1 response in vivo and in vitro, and its impact on periapical lesions risk and outcome, performed with a population of healthy controls (H; N = 283) and patients presenting periapical lesions (L; N = 188) or deep caries (DC; N = 152). | 30548981 | 2019 | ||||
|
0.010 | GeneticVariation | phenotype | BEFREE | Overall, SNPs in HSPA1L and HSPA6 showed significant allelic association with cases of deep caries and periapical lesions (P < .05). | 27567034 | 2016 | ||||
|
0.010 | GeneticVariation | phenotype | BEFREE | Overall, SNPs in HSPA1L and HSPA6 showed significant allelic association with cases of deep caries and periapical lesions (P < .05). | 27567034 | 2016 | ||||
|
0.010 | GeneticVariation | phenotype | BEFREE | A single-nucleotide polymorphism in IL1B (rs1143643) showed allelic (P = .02) and genotypic (P = .004) association with cases of deep caries and periapical lesions. | 25476976 | 2015 |