Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 50511
Gene Symbol: SYCP3
SYCP3 		0.010 Biomarker disease BEFREE But, SYCP3 transcripts were found in four tumor samples (moderately differentiated gemistocytic astrocytoma, pituitary adenoma, glioma and an ovarian tumor). 17920210 2007
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.310 Biomarker disease ORPHANET IDH1 and IDH2 mutations in gliomas. 19228619 2009
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.310 Biomarker disease ORPHANET Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas. 19554337 2009
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.310 Biomarker disease ORPHANET Molecular diagnostics of gliomas: state of the art. 20714900 2010
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.310 Biomarker disease ORPHANET Molecular classification of low-grade diffuse gliomas. 21075857 2010
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2 		0.300 Biomarker disease CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		0.300 Biomarker disease CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 23493
Gene Symbol: HEY2
HEY2 		0.300 Biomarker disease CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 4763
Gene Symbol: NF1
NF1 		0.300 Biomarker disease CTD_human Bioluminescent approaches for measuring tumor growth in a mouse model of neurofibromatosis. 20176786 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.300 Biomarker disease CTD_human Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression. 20188714 2010
Entrez Id: 4314
Gene Symbol: MMP3
MMP3 		0.300 Biomarker disease CTD_human Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression. 20188714 2010
Entrez Id: 10683
Gene Symbol: DLL3
DLL3 		0.300 Biomarker disease CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 23462
Gene Symbol: HEY1
HEY1 		0.300 Biomarker disease CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.260 Biomarker disease CTD_mouse Bioluminescent approaches for measuring tumor growth in a mouse model of neurofibromatosis. 20176786 2010
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.310 Biomarker disease ORPHANET Moving toward molecular classification of diffuse gliomas in adults. 23109653 2012
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 4763
Gene Symbol: NF1
NF1 		0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 57670
Gene Symbol: KIAA1549
KIAA1549 		0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2 		0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.310 Biomarker disease ORPHANET Correlation of IDH1/2 mutation with clinicopathologic factors and prognosis in anaplastic gliomas: a report of 203 patients from China. 24149775 2014
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.310 GeneticVariation disease BEFREE Here, we show that gemistocytic astrocytomas carry a lower frequency of IDH mutations than fibrillary astrocytomas (74% vs 92%; p = 0.0255) but have profiles similar to those of fibrillary astrocytomas with respect to TERT promoter mutations (5% vs 0%), 1p/19q loss (10% vs 8%), and loss of heterozygosity 10q (10% vs 12%). 25192052 2014
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.300 Biomarker disease CTD_human Expression of estrogen receptors, androgen receptor and steroid receptor coactivator-3 is negatively correlated to the differentiation of astrocytic tumors. 24680642 2014