Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8202
Gene Symbol: NCOA3
NCOA3
0.300 Biomarker disease CTD_human Expression of estrogen receptors, androgen receptor and steroid receptor coactivator-3 is negatively correlated to the differentiation of astrocytic tumors. 24680642 2014
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.300 Biomarker disease CTD_human Expression of estrogen receptors, androgen receptor and steroid receptor coactivator-3 is negatively correlated to the differentiation of astrocytic tumors. 24680642 2014
Entrez Id: 367
Gene Symbol: AR
AR
0.300 Biomarker disease CTD_human Expression of estrogen receptors, androgen receptor and steroid receptor coactivator-3 is negatively correlated to the differentiation of astrocytic tumors. 24680642 2014
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
0.300 Biomarker disease CTD_human Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma. 24705250 2014
Entrez Id: 110806263
Gene Symbol: LOC110806263
LOC110806263
0.010 GeneticVariation disease BEFREE Here, we show that gemistocytic astrocytomas carry a lower frequency of IDH mutations than fibrillary astrocytomas (74% vs 92%; p = 0.0255) but have profiles similar to those of fibrillary astrocytomas with respect to TERT promoter mutations (5% vs 0%), 1p/19q loss (10% vs 8%), and loss of heterozygosity 10q (10% vs 12%). 25192052 2014
Entrez Id: 6237
Gene Symbol: RRAS
RRAS
0.010 GeneticVariation disease BEFREE Alterations in RRAS and ERCC1 appear to be typical in gemistocytic astrocytomas and secondary glioblastomas, since they were not present in 49 fibrillary astrocytomas or 30 primary glioblastomas. 25192052 2014
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.010 GeneticVariation disease BEFREE Further screening showed RRAS homozygous deletion in 7 of 42 (17%) gemistocytic astrocytomas and in 3 of 24 (13%) IDH1 mutated secondary glioblastomas. 25192052 2014
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.010 Biomarker disease BEFREE Alterations in RRAS and ERCC1 appear to be typical in gemistocytic astrocytomas and secondary glioblastomas, since they were not present in 49 fibrillary astrocytomas or 30 primary glioblastomas. 25192052 2014