<b>Aim:</b> To study if cumulative glucocorticoid use could be related to cognitive impairment in rheumatoid arthritis (RA) patients.<b>Methods:</b> A sample of 60 RA patients and 64 controls were studied for the Mini Mental State Examination (MMSE) and depression scale (using CES-D or Center for Epidemiological Studies Depression scale).
<b>Background:</b> It remains unclear whether the degree of white matter tract damage or cerebral hypoperfusion can better predict global cognitive impairment in CADASIL.
<b>Background:</b> Neuron apoptosis mediated by hypoxia inducible factor 1α (HIF-1α) in hippocampus is one of the most important factors accounting for the chronic hypobaric hypoxia induced cognitive impairment.
<b>Background:</b> Neuron apoptosis mediated by hypoxia inducible factor 1α (HIF-1α) in hippocampus is one of the most important factors accounting for the chronic hypobaric hypoxia inducedcognitive impairment.
<b>Conclusion</b>: These findings suggest that astrocytic Cx43 may be a viable target for attenuating the demyelination and cognitive decline associated with chronic cerebral hypoperfusion.
<b>Conclusion</b>: These results suggest that UTI inhibits neuronal apoptosis in rat brain by attenuating increased expression of Aβ<sub>42</sub> and inflammatory cytokines, which may contribute to its alleviation of isoflurane-induced cognitive dysfunction in rats.
<b>Conclusion:</b> Independent-component analysis of <sup>18</sup>F-FDG PET data showed a gradual disruption of functional brain connectivity with progression of cognitive decline in AD.
<b>Conclusion:</b> The typical deposition of <sup>18</sup>F-AV1451 tau PET imaging in AD brain was found in amygdala, entorhinal cortex, fusiform and parahippocampus, and these regions were strongly associated with cognitive impairment and CSF biomarkers.
<b>Conclusion:</b> The typical deposition of <sup>18</sup>F-AV1451 tau PET imaging in AD brain was found in amygdala, entorhinal cortex, fusiform and parahippocampus, and these regions were strongly associated with cognitive impairment and CSF biomarkers.
<b>Conclusions:</b> In this dataset of only LGG patients treated with radiotherapy the hippocampus NTCP model did not perform as expected to predictcognitive decline based on dose to 40% of the bilateral hippocampus.
<b>Methods:</b> We reviewed studies reporting peripheral IL-6 with future cognitive decline, up to February 2017 by searching the PubMed, Science Direct, Scopus and Google Scholar databases.
<b>Objective</b>: The Word Memory Test (WMT) is a memory-based performance validity test (PVT) with adjusted interpretive criteria (Genuine Memory Impairment Profile; GMIP) proposed for those with cognitive impairment (CI).
<b>Objectives:</b> To determine the prevalence of cognitive impairment in patients with PD using Montreal Cognitive Assessment (MoCA), Comprehensive Trail Making Test (CTMT) and Parkinson's disease-cognitive rating scale (PDCRS), and its association with plasma α-synuclein and <i>ApoE</i> genetic polymorphisms.
<b>Results:</b> Current data on exercise-dependent BDNF changes for aging individuals in a course of cognitive impairment was summarized to investigate whether the exercise regulation of BDNF is effective to pronounce long term changes on executive controls.
<b>Theoretical background:</b> The Apolipoprotein E (APOE) ε4 genotype is known to be one of the strongest single-gene predictors for Alzheimer disease, which is characterized by widespread brain structural degeneration progressing along with cognitive impairment.
(<i>Theranostics</i> 2018; 8(19):5434-5451. doi:10.7150/thno.27882) that deficiency of TLR4 attenuates cognitive dysfunction and white matter injury by reducing autophagy and pro-inflammatory activation in microglia.
1.Available evidence confirms that the LRRK2 variant rs34637584 is associated with less cognitive impairment in people with PD.2.GBA variants rs76763715 and rs421016 are associated with more severe cognitive impairment in people with PD.3.The GBA variants rs76763715, rs421016, rs387906315 and rs80356773 have been significantly associated with the onset of depressive symptoms in PD.