Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
Entrez Id: 246778
Gene Symbol: IL27
IL27
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
Entrez Id: 29949
Gene Symbol: IL19
IL19
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.300 Biomarker disease CTD_human IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. 19119414 2009
Entrez Id: 3240
Gene Symbol: HP
HP
0.300 Biomarker disease CTD_human Impact of diabetes mellitus on the relationships between iron-, inflammatory- and oxidative stress status. 16506275 2006
Entrez Id: 1129
Gene Symbol: CHRM2
CHRM2
0.300 Biomarker disease CTD_human Increase of cardiac M2-muscarinic receptor gene expression in type-1 but not in type-2 diabetic rats. 18603373 2008
Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
0.300 Biomarker disease CTD_human Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes. 18025464 2007
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8
0.300 Biomarker disease CTD_human Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes. 18025464 2007
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
0.300 Biomarker disease CTD_human Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids. 21190368 2011
Entrez Id: 3630
Gene Symbol: INS
INS
0.500 Biomarker disease CTD_mouse Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice. 29420703 2018
Entrez Id: 6556
Gene Symbol: SLC11A1
SLC11A1
0.300 Biomarker disease CTD_human Iron and infection: effects of host iron status and the iron-regulatory genes haptoglobin and NRAMP1 (SLC11A1) on host-pathogen interactions in tuberculosis and HIV. 16597321 2006
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.300 Biomarker disease CTD_human Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. 17676041 2007
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.300 Biomarker disease CTD_human Mechanism of BDE209-induced impaired glucose homeostasis based on gene microarray analysis of adult rat liver. 23640034 2013
Entrez Id: 114904
Gene Symbol: C1QTNF6
C1QTNF6
0.300 Biomarker disease CTD_human Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. 18978792 2008
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
0.300 Biomarker disease CTD_human Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. 18978792 2008
Entrez Id: 1512
Gene Symbol: CTSH
CTSH
0.300 Biomarker disease CTD_human Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. 18978792 2008
Entrez Id: 5588
Gene Symbol: PRKCQ
PRKCQ
0.300 Biomarker disease CTD_human Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. 18978792 2008
Entrez Id: 55315
Gene Symbol: SLC29A3
SLC29A3
0.300 Biomarker disease CTD_human Mutations in SLC29A3, encoding an equilibrative nucleoside transporter ENT3, cause a familial histiocytosis syndrome (Faisalabad histiocytosis) and familial Rosai-Dorfman disease. 20140240 2010
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.300 Biomarker disease CTD_human Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes. 21340626 2011
Entrez Id: 6364
Gene Symbol: CCL20
CCL20
0.300 Therapeutic disease CTD_human Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes. 21340626 2011
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
0.300 Therapeutic disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
0.300 Biomarker disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3
0.300 Biomarker disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 100506742
Gene Symbol: CASP12
CASP12
0.300 Biomarker disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.300 Therapeutic disease CTD_human Reducing blood glucose levels in TIDM mice with an orally administered extract of sericin from hIGF-I-transgenic silkworm cocoons. 24632065 2014