Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57105
Gene Symbol: CYSLTR2
CYSLTR2 		0.400 SomaticCausalMutation disease ORPHANET Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma. 27089179 2016
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1 		0.400 Biomarker disease ORPHANET SF3B1 mutations are associated with alternative splicing in uveal melanoma. 23861464 2013
Entrez Id: 2767
Gene Symbol: GNA11
GNA11 		0.400 SomaticCausalMutation disease ORPHANET Genomic, prognostic, and cell-signaling advances in uveal melanoma. 23714557 2013
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ 		0.400 SomaticCausalMutation disease ORPHANET Genomic, prognostic, and cell-signaling advances in uveal melanoma. 23714557 2013
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1 		0.400 Biomarker disease ORPHANET Genomic, prognostic, and cell-signaling advances in uveal melanoma. 23714557 2013
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		0.400 GermlineCausalMutation disease ORPHANET Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers. 21941004 2011
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ 		0.400 SomaticCausalMutation disease ORPHANET Mutations in GNA11 in uveal melanoma. 21083380 2010
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		0.400 SomaticCausalMutation disease ORPHANET Frequent mutation of BAP1 in metastasizing uveal melanomas. 21051595 2010
Entrez Id: 2767
Gene Symbol: GNA11
GNA11 		0.400 SomaticCausalMutation disease ORPHANET Mutations in GNA11 in uveal melanoma. 21083380 2010
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ 		0.400 Biomarker disease HPO
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		0.400 Biomarker disease HPO
Entrez Id: 2767
Gene Symbol: GNA11
GNA11 		0.400 Biomarker disease HPO
Entrez Id: 57105
Gene Symbol: CYSLTR2
CYSLTR2 		0.400 Biomarker disease HPO
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1 		0.400 Biomarker disease HPO
Entrez Id: 4921
Gene Symbol: DDR2
DDR2 		0.100 GeneticVariation disease GWASCAT Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. 31626034 2020
Entrez Id: 753
Gene Symbol: LDLRAD4
LDLRAD4 		0.100 GeneticVariation disease GWASCAT Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. 31626034 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.020 GeneticVariation disease BEFREE To our knowledge, for the first time, here we report a case of choroidal melanoma harboring the BRAF mutation (V600E). 16410717 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.020 AlteredExpression disease BEFREE Chromosomal abnormalities, p53 and Bcl-2 expression and clinical outcome in choroidal melanoma. 15577317 2004
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.020 GeneticVariation disease BEFREE We show that three cell lines (OCM-1, MKT-BR, and SP-6.5) derived from human choroidal melanoma, the most frequent primary ocular neoplasm in humans, express B-Raf containing the V599E mutation. 12917419 2003
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.020 GeneticVariation disease BEFREE Increased expression and mutation of p53 in choroidal melanoma. 1419633 1992
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2 		0.010 GeneticVariation disease BEFREE Patients diagnosed with iris, ciliary body or choroidal melanoma with high-risk tumour cytogenetics (monosomy 3) were offered adjuvant treatment with low-dose DTIC and IFN-α-2b following primary therapy. 31371315 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.010 Biomarker disease BEFREE VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway. 31380420 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		0.010 Biomarker disease BEFREE VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway. 31380420 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		0.010 Biomarker disease BEFREE VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway. 31380420 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.010 AlteredExpression disease BEFREE VEGF protein was expressed in CM in all 20 cases of CM, especially along the VM. 31380420 2019