Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
0.300 Biomarker phenotype CTD_human p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure. 10436046 1999
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
0.300 Biomarker phenotype CTD_human Dopaminergic modulation of pilocarpine-induced motor seizures in the rat: the role of hippocampal dopamine D1 receptors. 1451735 1992
Entrez Id: 11284
Gene Symbol: PNKP
PNKP
0.300 Biomarker phenotype CTD_human Mutations in PNKP cause microcephaly, seizures and defects in DNA repair. 20118933 2010
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
0.300 Biomarker phenotype CTD_human Mechanisms of morphine enhancement of spontaneous seizure activity. 18042875 2007
Entrez Id: 328
Gene Symbol: APEX1
APEX1
0.300 Biomarker phenotype CTD_human Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures. 20446108 2010
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.300 Biomarker phenotype CTD_human Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures. 20446108 2010
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
0.300 Biomarker phenotype CTD_human The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice. 15275829 2004
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 847
Gene Symbol: CAT
CAT
0.300 Biomarker phenotype CTD_human Neuroprotective actions of vitamin C related to decreased lipid peroxidation and increased catalase activity in adult rats after pilocarpine-induced seizures. 18096215 2008
Entrez Id: 5020
Gene Symbol: OXT
OXT
0.300 Biomarker phenotype CTD_human "Oxytocin, ""salting out,"" and water intoxication." 5067144 1972
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5
0.300 Biomarker phenotype CTD_human A thallium transport FLIPR-based assay for the identification of KCC2-positive modulators. 20086212 2010
Entrez Id: 2353
Gene Symbol: FOS
FOS
0.300 Biomarker phenotype CTD_human C-Fos expression as a molecular marker in corticotropin-releasing factor-induced seizures. 8923670 1996
Entrez Id: 5020
Gene Symbol: OXT
OXT
0.300 Biomarker phenotype CTD_human Syntocinon induced convulsion. 5493616 1970
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
0.300 Biomarker phenotype CTD_human A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model. 27469509 2016
Entrez Id: 1128
Gene Symbol: CHRM1
CHRM1
0.300 Biomarker phenotype CTD_human The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures. 12091480 2002
Entrez Id: 847
Gene Symbol: CAT
CAT
0.300 Biomarker phenotype CTD_human Investigation of oxidative stress involvement in hippocampus in epilepsy model induced by pilocarpine. 19616071 2009
Entrez Id: 57534
Gene Symbol: MIB1
MIB1
0.300 Biomarker phenotype CTD_human Spontaneous seizures and altered gene expression in GABA signaling pathways in a mind bomb mutant zebrafish. 20943912 2010
Entrez Id: 6750
Gene Symbol: SST
SST
0.300 Biomarker phenotype CTD_human Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. 16771832 2006
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.300 Biomarker phenotype CTD_human Changes in brain interleukin-1beta following the coadministration of norfloxacin with biphenylacetic acid in rats. 16824509 2006
Entrez Id: 2353
Gene Symbol: FOS
FOS
0.300 Biomarker phenotype CTD_human Spontaneous recurrent seizures after pilocarpine-induced status epilepticus activate calbindin-immunoreactive hilar cells of the rat dentate gyrus. 11955713 2002
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
0.300 Biomarker phenotype CTD_human 7-Nitro indazole, an inhibitor of neuronal nitric oxide synthase, attenuates pilocarpine-induced seizures. 8749039 1995
Entrez Id: 10280
Gene Symbol: SIGMAR1
SIGMAR1
0.300 Biomarker phenotype CTD_human Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters. 11684152 2001
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
0.300 Biomarker phenotype CTD_human Adenosine A2A receptor deficient mice are partially resistant to limbic seizures. 19488739 2009
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker phenotype CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
Entrez Id: 54715
Gene Symbol: RBFOX1
RBFOX1
0.300 Biomarker phenotype CTD_human The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain. 21623373 2011