Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker phenotype CTD_human Increased sensitivity to nicotine-induced seizures in mice heterozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor. 11893908 2002
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker phenotype CTD_human Genetic and pharmacological strategies identify a behavioral function of neuronal nicotinic receptors. 10942032 2000
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker phenotype CTD_human Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures. 14996991 2004
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4 		0.300 Biomarker phenotype CTD_human Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures. 14996991 2004
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4 		0.300 Biomarker phenotype CTD_human The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice. 15275829 2004
Entrez Id: 1191
Gene Symbol: CLU
CLU 		0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 54805
Gene Symbol: CNNM2
CNNM2 		0.300 Biomarker phenotype CTD_human Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2). 23027747 2012
Entrez Id: 1268
Gene Symbol: CNR1
CNR1 		0.300 Biomarker phenotype CTD_human The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy. 12954810 2003
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human ACTH does not control neonatal seizures induced by administration of exogenous corticotropin-releasing hormone. 7821275 1995
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human Some endorphin derivatives and hydrocortisone prevent EEG limbic seizures induced by corticotropin-releasing factor in rabbits. 1700951 1991
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human Corticotropin-releasing hormone-induced seizures in infant rats originate in the amygdala. 1596084 1992
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human Increased expression of gamma-aminobutyric acid transporter-1 in the forebrain of infant rats with corticotropin-releasing hormone-induced seizures but not in those with hyperthermia-induced seizures. 11074187 2000
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human C-Fos expression as a molecular marker in corticotropin-releasing factor-induced seizures. 8923670 1996
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human Corticotropin-releasing hormone is a rapid and potent convulsant in the infant rat. 1914160 1991
Entrez Id: 1583
Gene Symbol: CYP11A1
CYP11A1 		0.300 Therapeutic phenotype CTD_human Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period. 19125849 2009
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		0.300 Biomarker phenotype CTD_human Dopaminergic modulation of pilocarpine-induced motor seizures in the rat: the role of hippocampal dopamine D1 receptors. 1451735 1992
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		0.300 Biomarker phenotype CTD_human Dopamine D1 and D2 receptors mediate opposite functions in seizures induced by lithium-pilocarpine. 1829682 1991
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human Dopamine D2 receptor signaling controls neuronal cell death induced by muscarinic and glutamatergic drugs. 11860278 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Therapeutic phenotype CTD_human Dopamine D1 and D2 receptors mediate opposite functions in seizures induced by lithium-pilocarpine. 1829682 1991
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Therapeutic phenotype CTD_human Dopamine D2 receptor signaling controls neuronal cell death induced by muscarinic and glutamatergic drugs. 11860278 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human Effects of dopamine D3 receptor agonists on pilocarpine-induced limbic seizures in the rat. 7936204 1994
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human Dopamine D1 and D2 receptors mediate opposite functions in seizures induced by lithium-pilocarpine. 1829682 1991
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Therapeutic phenotype CTD_human Effects of dopamine D3 receptor agonists on pilocarpine-induced limbic seizures in the rat. 7936204 1994
Entrez Id: 1814
Gene Symbol: DRD3
DRD3 		0.300 Therapeutic phenotype CTD_human The dopamine D3/D2 agonist (+)-PD-128,907 [(R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol)] protects against acute and cocaine-kindled seizures in mice: further evidence for the involvement of D3 receptors. 18566292 2008
Entrez Id: 2166
Gene Symbol: FAAH
FAAH 		0.300 Therapeutic phenotype CTD_human Enhancement of endocannabinoid signaling protects against cocaine-induced neurotoxicity. 25933444 2015