Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4204
Gene Symbol: MECP2
MECP2 		0.300 Biomarker phenotype CTD_human Novel variants identified in methyl-CpG-binding domain genes in autistic individuals. 19921286 2010
Entrez Id: 2784
Gene Symbol: GNB3
GNB3 		0.300 Biomarker phenotype CTD_human G-protein gene 825C>T polymorphism is associated with response to clozapine in Brazilian schizophrenics. 18855531 2008
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker phenotype CTD_human Increased sensitivity to nicotine-induced seizures in mice heterozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor. 11893908 2002
Entrez Id: 2353
Gene Symbol: FOS
FOS 		0.300 Biomarker phenotype CTD_human Spatial and temporal evolution of neuronal activation, stress and injury in lithium-pilocarpine seizures in adult rats. 9630518 1998
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Biomarker phenotype CTD_human [A case of Aicardi syndrome with moderate psychomotor retardation]. 2169275 1990
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		0.300 Biomarker phenotype CTD_human GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier. 9462754 1998
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker phenotype CTD_human Pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats. 19941057 2010
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Biomarker phenotype CTD_human Neuroprotective actions of vitamin C related to decreased lipid peroxidation and increased catalase activity in adult rats after pilocarpine-induced seizures. 18096215 2008
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.300 Biomarker phenotype CTD_human Pilocarpine-induced status epilepticus increases cell proliferation in the dentate gyrus of adult rats via a 5-HT1A receptor-dependent mechanism. 12646302 2003
Entrez Id: 2572
Gene Symbol: GAD2
GAD2 		0.300 Biomarker phenotype CTD_human Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures. 8954991 1996
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker phenotype CTD_human Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures. 14996991 2004
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		0.300 Biomarker phenotype CTD_human Autosomal dominant glut-1 deficiency syndrome and familial epilepsy. 11603379 2001
Entrez Id: 2897
Gene Symbol: GRIK1
GRIK1 		0.300 Biomarker phenotype CTD_human Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures. 12080343 2002
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4 		0.300 Biomarker phenotype CTD_human Genetic and pharmacological strategies identify a behavioral function of neuronal nicotinic receptors. 10942032 2000
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1 		0.300 Biomarker phenotype CTD_human Mechanisms of morphine enhancement of spontaneous seizure activity. 18042875 2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human Dopamine D2 receptor signaling controls neuronal cell death induced by muscarinic and glutamatergic drugs. 11860278 2002
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.300 Biomarker phenotype CTD_human Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. 9073163 1997
Entrez Id: 1128
Gene Symbol: CHRM1
CHRM1 		0.300 Biomarker phenotype CTD_human The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures. 12091480 2002
Entrez Id: 5428
Gene Symbol: POLG
POLG 		0.300 Biomarker phenotype CTD_human POLG DNA testing as an emerging standard of care before instituting valproic acid therapy for pediatric seizure disorders. 20138553 2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.300 Biomarker phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 6505
Gene Symbol: SLC1A1
SLC1A1 		0.300 Biomarker phenotype CTD_human Caffeine-induced inhibition of the activity of glutamate transporter type 3 expressed in Xenopus oocytes. 23262392 2013
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B 		0.300 Biomarker phenotype CTD_human The role of the central serotonergic system in pilocarpine-induced seizures: receptor mechanisms. 2533336 1989
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human C-Fos expression as a molecular marker in corticotropin-releasing factor-induced seizures. 8923670 1996
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker phenotype CTD_human Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. 16194568 2005
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker phenotype CTD_human Sigma 1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y. 18005069 2007