Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Therapeutic phenotype CTD_human Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine. 20971807 2011
Entrez Id: 5978
Gene Symbol: REST
REST 		0.300 Therapeutic phenotype CTD_human Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy. 21905079 2011
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		0.300 Therapeutic phenotype CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		0.300 Biomarker phenotype CTD_human Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex. 21062901 2011
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.300 Biomarker phenotype CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
Entrez Id: 54715
Gene Symbol: RBFOX1
RBFOX1 		0.300 Biomarker phenotype CTD_human The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain. 21623373 2011
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Biomarker phenotype CTD_human Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum. 20592767 2011
Entrez Id: 4204
Gene Symbol: MECP2
MECP2 		0.300 Biomarker phenotype CTD_human Novel variants identified in methyl-CpG-binding domain genes in autistic individuals. 19921286 2010
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker phenotype CTD_human Pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats. 19941057 2010
Entrez Id: 5428
Gene Symbol: POLG
POLG 		0.300 Biomarker phenotype CTD_human POLG DNA testing as an emerging standard of care before instituting valproic acid therapy for pediatric seizure disorders. 20138553 2010
Entrez Id: 5428
Gene Symbol: POLG
POLG 		0.300 Biomarker phenotype CTD_human Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures. 20446108 2010
Entrez Id: 1103
Gene Symbol: CHAT
CHAT 		0.300 Biomarker phenotype CTD_human Pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats. 19941057 2010
Entrez Id: 6750
Gene Symbol: SST
SST 		0.300 Therapeutic phenotype CTD_human Hippocampal sst(1) receptors are autoreceptors and do not affect seizures in rats. 20134357 2010
Entrez Id: 6547
Gene Symbol: SLC8A3
SLC8A3 		0.300 Biomarker phenotype CTD_human Blockade of the sodium calcium exchanger exhibits anticonvulsant activity in a pilocarpine model of acute seizures in rats. 20888801 2010
Entrez Id: 6750
Gene Symbol: SST
SST 		0.300 Biomarker phenotype CTD_human Hippocampal sst(1) receptors are autoreceptors and do not affect seizures in rats. 20134357 2010
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		0.300 Biomarker phenotype CTD_human Lipoic acid alters delta-aminolevulinic dehydratase, glutathione peroxidase and Na+,K+-ATPase activities and glutathione-reduced levels in rat hippocampus after pilocarpine-induced seizures. 19798568 2010
Entrez Id: 328
Gene Symbol: APEX1
APEX1 		0.300 Biomarker phenotype CTD_human Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures. 20446108 2010
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5 		0.300 Biomarker phenotype CTD_human A thallium transport FLIPR-based assay for the identification of KCC2-positive modulators. 20086212 2010
Entrez Id: 11284
Gene Symbol: PNKP
PNKP 		0.300 Biomarker phenotype CTD_human Mutations in PNKP cause microcephaly, seizures and defects in DNA repair. 20118933 2010
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Biomarker phenotype CTD_human Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures. 20446108 2010
Entrez Id: 5066
Gene Symbol: PAM
PAM 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1 		0.300 Biomarker phenotype CTD_human Blockade of the sodium calcium exchanger exhibits anticonvulsant activity in a pilocarpine model of acute seizures in rats. 20888801 2010
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Therapeutic phenotype CTD_human Pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats. 19941057 2010
Entrez Id: 348980
Gene Symbol: HCN1
HCN1 		0.300 Biomarker phenotype CTD_human Increased seizure severity and seizure-related death in mice lacking HCN1 channels. 20384728 2010
Entrez Id: 57534
Gene Symbol: MIB1
MIB1 		0.300 Biomarker phenotype CTD_human Spontaneous seizures and altered gene expression in GABA signaling pathways in a mind bomb mutant zebrafish. 20943912 2010