Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10309
Gene Symbol: CCNO
CCNO
0.400 Biomarker group CTD_human Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia. 24747639 2014
Entrez Id: 10309
Gene Symbol: CCNO
CCNO
0.400 Biomarker group HPO
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
0.310 GeneticVariation group BEFREE Association between the BclI glucocorticoid receptor polymorphism and smoking in a sample of patients with obstructive airway disease. 17407502 2007
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
0.310 Biomarker group CTD_human Glucocorticoid receptor mRNA levels in bronchial epithelial cells of patients with COPD: influence of glucocorticoids. 9926163 1998
Entrez Id: 2294
Gene Symbol: FOXF1
FOXF1
0.300 Biomarker group CTD_human Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene. 18421012 2008
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE Recent reports have identified pain as a comorbidity in obstructive lung diseases, but data regarding pain in certain obstructive lung diseases such as COPD and bronchiectasis vs. healthy controls and differences in pain between these chronic lung diseases are limited. 30655003 2020
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE We conclude that peri- and postmenopausal women with obstructive lung diseases had a decreased serum concentration of vitamin D. Furthermore, vitamin D and body mineral density were appreciably lower in women with COPD than those with asthma. 29564774 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE COPD is a common irreversible obstructive airway disease. 30349224 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE The main reason for nonprescription of BB was a concomitant obstructive airway disease (asthma or COPD) but was a concomitant chronic kidney disease for nonprescription of RAS blocker. 31339629 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE Patients with COPD were recruited from 16 hospitals of the Korean Obstructive Lung Disease cohort (n=395) and COPD in Dusty Area cohort (n=234) of Kangwon University Hospital. 30464441 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 GeneticVariation group BEFREE <b>Patients and methods:</b> The data of 18 patients with OLD (16 with COPD, two with asthma COPD overlap), 11 with ILD, and 24 healthy volunteers, whose respiratory impedance was measured using a MostGraph-01 and other pulmonary functions including Cst and lung resistance (R<sub>L</sub>) were measured on the same day and were retrospectively collected and compared. 31213791 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE Asthma and COPD are the most common obstructive lung diseases characterized by inflammation in the lower airways which contribute to airflow limitation. 27739024 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE The purpose of the current study was to determine the association between sedentary time and physical activity with clinically relevant health outcomes among adults with impaired spirometry and those with or without self-reported obstructive lung disease (asthma or COPD). 29879930 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE A new version of the Russian Respiratory Society guidelines released at the end of 2016 was based on the proposal by Global Initiative for Obstructive Lung Disease but adapted to the characteristics of the Russian health system and included an algorithm of pharmacologic treatment of COPD. 29386887 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE This placebo-controlled, double-blind, parallel-design trial included patients with COPD and Global Initiative for Obstructive Lung Disease grade 1 to 2 who were living below 800 m. Patients were randomized to receive dexamethasone (8 mg/d) or placebo starting on the day before ascent and while staying in a high-altitude clinic at 3,100 m for 2 days. 29909285 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE The COPD classification proposed by the Global Initiative for Obstructive Lung Disease was recently revised, and the A to D grouping is now based on symptoms and exacerbations only. 29413512 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE The more severe the COPD in the Global Initiative for Obstructive Lung Disease stages, the more severe the CAD and the more calcified coronary plaques (<i>P</i> < 0.0001). 29983554 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE Treatment of obstructive lung disease may have greater effect on cardiac function than treatment of pulmonary vascular disease in most COPD patients KEY POINTS: • Pulmonary pulse wave velocity (PWV) is elevated in COPD. 29488084 2018
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 GeneticVariation group BEFREE Regular use of inhaled corticosteroids (ICS) in patients with obstructive lung diseases has been associated with a higher risk of pneumonia, particularly in COPD. 28617814 2017
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 GeneticVariation group BEFREE Impact of overweight and obesity on acute exacerbations of COPD - subgroup analysis of the Taiwan Obstructive Lung Disease cohort. 28979114 2017
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 GeneticVariation group BEFREE Following confirmative spirometry, the 949 individuals were diagnosed as having COPD (51%), asthma (3%), and no obstructive lung disease (45%). 28831249 2017
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE We excluded subjects with history of both COPD and heart failure and patients with obstructive sleep apnea and obstructive lung disease other than COPD. 29391845 2017
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE A network of COPD health economic modelers used data from five COPD data sources - two population-based studies (COPDGene<sup>®</sup> and The Obstructive Lung Disease in Norrbotten), one primary care study (RECODE), and two studies in secondary care (Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoint and UPLIFT) - to estimate and validate several prediction models for total and severe exacerbations (= hospitalization). 29138546 2017
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker group BEFREE We hypothesized that a lower FEV(1) in these subjects is a potential marker of an increased susceptibility to obstructive lung disease such as asthma and COPD. 21468164 2011
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 GeneticVariation group BEFREE Lower values of FEF(25-75) and FEF(25-75)/FVC in non-smoking first degree relatives of early onset COPD probands than in controls suggest a genetic susceptibility to develop obstructive lung disease, independent of smoking, which is magnified by exposure to deleterious environments as suggested by the further decrements in FEF(25-75) and FEF(25-75)/FVC seen in smoking first degree relatives. 15115866 2004