Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR The functional impact of variants of uncertain significance in BRCA2. 29988080 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma. 30425037 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 GeneticVariation disease CLINVAR Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation. 30765603 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 GeneticVariation disease CLINVAR Quantifying BRCA1 and BRCA2 mRNA Isoform Expression Levels in Single Cells. 30736279 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation. 30765603 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Age-adjusted association of homologous recombination genes with ovarian cancer using clinical exomes as controls. 31341520 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Biallelic germline BRCA1 mutations in a patient with early onset breast cancer, mild Fanconi anemia-like phenotype, and no chromosome fragility. 31347298 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Mis-splicing in breast cancer: identification of pathogenic BRCA2 variants by systematic minigene assays. 30883759 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Population and breast cancer patients' analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population. 30630528 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Combining Homologous Recombination and Phosphopeptide-binding Data to Predict the Impact of BRCA1 BRCT Variants on Cancer Risk. 30257991 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR BRCA1 and BRCA2 mutations and clinical interpretation in 398 ovarian cancer patients: comparison with breast cancer variants in a similar population. 30103829 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Mechanism for survival of homozygous nonsense mutations in the tumor suppressor gene BRCA1. 29712865 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 GeneticVariation disease CLINVAR Intraductal/ductal histology and lymphovascular invasion are associated with germline DNA-repair gene mutations in prostate cancer. 29368341 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Characterization of spliceogenic variants located in regions linked to high levels of alternative splicing: BRCA2 c.7976+5G > T as a case study. 29969168 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia. 28993434 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Full in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer. 29707112 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Mutation analysis of BRCA1/2 mutations with special reference to polymorphic SNPs in Indian breast cancer patients. 29785135 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Dealing With BRCA1/2 Unclassified Variants in a Cancer Genetics Clinic: Does Cosegregation Analysis Help? 30254663 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 GeneticVariation disease CLINVAR Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches. 29394989 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR BRCA germline mutations in an unselected nationwide cohort of Chinese patients with ovarian cancer and healthy controls. 30078507 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Clinical genetic testing outcome with multi-gene panel in Asian patients with multiple primary cancers. 30093976 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Data sharing as a national quality improvement program: reporting on BRCA1 and BRCA2 variant-interpretation comparisons through the Canadian Open Genetics Repository (COGR). 28726806 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 GeneticVariation disease CLINVAR Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer. 29983880 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 GeneticVariation disease CLINVAR Validation and Implementation of BRCA1/2 Variant Screening in Ovarian Tumor Tissue. 29936257 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Intraductal/ductal histology and lymphovascular invasion are associated with germline DNA-repair gene mutations in prostate cancer. 29368341 2018