| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.010 | Biomarker | disease | BEFREE | Elacridar, an ABCG2 and ABCB1 inhibitor, significantly increases the efficacy of dasatinib in brainstem glioma-bearing ABC WT mice (42 vs. 59 days). | 26883271 | 2016 | ||||
|
0.010 | Biomarker | disease | BEFREE | Systematic delivery of MSC-hTRAIL can prolong the survival of brainstem glioma-bearing mice, presumably through a dual-targeted effect of membrane-spanned, TRAIL-engineered MSCs in the tumor microenvironment. | 19687708 | 2009 | ||||
|
0.010 | AlteredExpression | disease | BEFREE | The results indicate that Pax3 regulates GFAP expression, and that Pax3 may contribute to the evolution of BGSCs towards malignancy. | 27432276 | 2016 | ||||
|
0.010 | AlteredExpression | disease | BEFREE | Our research revealed that miR-20a and miR-106b (known to be closely related) were the two most robust upregulated miRNAs in pediatric BSG compared to adult subtype. | 22825541 | 2012 | ||||
|
0.010 | Biomarker | disease | BEFREE | In an effort to elucidate unique characteristics of BSG, we conducted expression analysis of mouse PDGF-B-driven BSG and CG initiated in Nestin progenitor cells and identified a short list of expression changes specific to the brainstem gliomagenesis process, including abnormal upregulation of paired box 3 (Pax3). | 25330836 | 2014 | ||||
|
0.010 | Biomarker | disease | BEFREE | PD-L1 staining was detected in 59.7% of brainstem glioma specimens (37/62). | 29137285 | 2017 | ||||
|
0.010 | Biomarker | disease | BEFREE | Development of a novel imaging agent using peptide-coated gold nanoparticles toward brain glioma stem cell marker CD133. | 27721007 | 2017 | ||||
|
0.010 | AlteredExpression | disease | BEFREE | In this study, the expression of β-catenin and E- and N-cadherin was detected in 40 brainstem glioma samples using immunochemistry and was further analyzed in 18 samples using reverse transcription-polymerase chain reaction. | 23240619 | 2013 |