Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 80790
Gene Symbol: CMIP
CMIP
0.010 AlteredExpression disease BEFREE Elevated expression of CMIP was associated with poor clinicopathological features including tumor size, lymph node metastasis and clinical stage in HER2 positive gastric cancer patients. 31822364 2020
Entrez Id: 6781
Gene Symbol: STC1
STC1
0.010 AlteredExpression disease BEFREE MLL2 promotes cancer cell lymph node metastasis by interacting with RelA and facilitating STC1 transcription. 31676369 2020
Entrez Id: 100126296
Gene Symbol: MIR298
MIR298
0.010 AlteredExpression disease BEFREE Also, the aberrant level of miR-298 contributed with CRC tumor differentiation, TNM stage and lymph node metastasis (p < .001), and independently associated with poor survival of CRC patients (p < .029; hazard ratio: 1.292; 95% confidence interval: 0.339-2.184). 31621072 2020
Entrez Id: 10093
Gene Symbol: ARPC4
ARPC4
0.010 Biomarker disease BEFREE This study was to identify the correlation between ARPC4 and lymph node metastasis, and to determine the role of ARPC4 in the invasive migration of T24 bladder cancer cells. 31190401 2020
Entrez Id: 9476
Gene Symbol: NAPSA
NAPSA
0.010 AlteredExpression disease BEFREE The clinicopathological analysis of papillary thyroid carcinomas showed that the expression of napsin A was positively correlated with lymph node metastasis (p = 0.030). 31788765 2020
Entrez Id: 105377871
Gene Symbol: LOC105377871
LOC105377871
0.010 GeneticVariation disease BEFREE Results showed that in northwest Chinese Han population, SNP rs17530068 (LOC105377871) increases the risk of breast cancer and SNP rs4784227 (CASC16) promotes lymph node metastasis in breast cancer patients. 31655495 2020
Entrez Id: 3803
Gene Symbol: KIR2DL2
KIR2DL2
0.010 GeneticVariation disease BEFREE The higher proportion of LNM in carriers of KIR2DL2 and carriers of 5 iKIRs, suggested that inhibitory KIRs are associated with metastatic risk. 31751561 2020
Entrez Id: 6298
Gene Symbol: SAI1
SAI1
0.010 AlteredExpression disease BEFREE Mts1 was highly expressed in patients with thyroid cancer and high Mts1 levels were related to poor prognoses such as lymph node metastasis. 31467231 2020
Entrez Id: 23671
Gene Symbol: TMEFF2
TMEFF2
0.010 AlteredExpression disease BEFREE The expression of TMEFF2 in EC was significantly higher than that in atypical hyperplasia and normal endometrium, the high expression of TMEFF2 was correlated with advanced stage, poor differentiation, and lymph node metastasis, and also predicted a poor prognosis of EC. 31610211 2020
Entrez Id: 4084
Gene Symbol: MXD1
MXD1
0.010 AlteredExpression disease BEFREE High miRNA-382 expression, MXD1 expression, and combined miRNA-382-5p and low MXD1 expression were significantly associated with advanced tumor stage and the presence of lymph node metastasis (all P < 0.05). 31635836 2020
Entrez Id: 100302158
Gene Symbol: MIR1231
MIR1231
0.010 AlteredExpression disease BEFREE Downregulation of miR-1231 was significantly associated with lymph node metastasis, higher TNM stage, higher clinical stage, and shorter overall survival. 31822000 2020
Entrez Id: 140828
Gene Symbol: LINC00261
LINC00261
0.010 AlteredExpression disease BEFREE Up-regulation of LINC00261 was related to larger tumor size (p = 0.009), positive lymph node metastasis (p = 0.021), advanced TNM stages (p = 0.017) and higher postoperative recurrence (p = 0.009) for CCA patients. 31812439 2020
Entrez Id: 643714
Gene Symbol: CASC16
CASC16
0.010 GeneticVariation disease BEFREE Results showed that in northwest Chinese Han population, SNP rs17530068 (LOC105377871) increases the risk of breast cancer and SNP rs4784227 (CASC16) promotes lymph node metastasis in breast cancer patients. 31655495 2020
Entrez Id: 29887
Gene Symbol: SNX10
SNX10
0.010 AlteredExpression disease BEFREE Here, we report a significant down regulation of SNX10 (sorting nexin 10) in human CRC tissues, which is closely related to tumor differentiation, TNM stage, lymph node metastasis and survival period. 31208298 2020
Entrez Id: 56667
Gene Symbol: MUC13
MUC13
0.010 AlteredExpression disease BEFREE MUC13 overexpression positively correlated with clinicopathological characteristics of iCCA, such as vascular invasion and lymph node metastasis, and was independently associated with poor survival. 31837357 2020
Entrez Id: 6355
Gene Symbol: CCL8
CCL8
0.010 Biomarker disease BEFREE Within test dataset GSE25065, RSAD2, and CCL8 were correlated with tumor stage, grade, and lymph node metastases, whereas HERC5 was correlated with lymph node metastases and tumor grade. 31225658 2020
Entrez Id: 11328
Gene Symbol: FKBP9
FKBP9
0.010 AlteredExpression disease BEFREE High expression of FKBP9 was related with lymph node metastasis (P = 0.022) and distant metastasis (P = 0.028). 31780055 2020
Entrez Id: 9918
Gene Symbol: NCAPD2
NCAPD2
0.010 AlteredExpression disease BEFREE NCAPD2 expression was positively associated with lymph node metastasis (P = 3.84 × 10<sup>-06</sup>), poor overall survival (P = 0.0033), and worse disease-free survival (P = 0.0013) of patients with TNBC. 31610177 2020
Entrez Id: 54555
Gene Symbol: DDX49
DDX49
0.010 Biomarker disease BEFREE These findings suggested that DDX49 may be useful as a novel biomarker of lymph node metastases and therapeutic target for lung cancer metastasis. 31749282 2020
Entrez Id: 23002
Gene Symbol: DAAM1
DAAM1
0.010 AlteredExpression disease BEFREE The high expression of DAAM1 in BrCa tissues was significantly associated with lymph-node metastasis. 31757662 2020
Entrez Id: 114041
Gene Symbol: B3GALT5-AS1
B3GALT5-AS1
0.010 AlteredExpression disease BEFREE Further exploration validated that high serum B3GALT5-AS1 level was related to TNM stage (P = .024), and lymph node metastasis (P = .023). 31338903 2020
Entrez Id: 7414
Gene Symbol: VCL
VCL
0.010 AlteredExpression disease BEFREE Pearson correlation analysis showed that vinculin expression was significantly correlated with tumor-node-metastasis (TNM) stage and lymph node metastasis in NSCLC. 30947597 2020
Entrez Id: 3482
Gene Symbol: IGF2R
IGF2R
0.010 AlteredExpression disease BEFREE Immunohistochemistry (IHC) and Cox regression analysis showed low IGF2R expression were significantly associated with more advanced histological grade; high clinical stage; lymph node metastasis and poorer overall survival for patients with bladder cancer. 31847523 2020
Entrez Id: 51191
Gene Symbol: HERC5
HERC5
0.010 Biomarker disease BEFREE Within test dataset GSE25065, RSAD2, and CCL8 were correlated with tumor stage, grade, and lymph node metastases, whereas HERC5 was correlated with lymph node metastases and tumor grade. 31225658 2020
Entrez Id: 3577
Gene Symbol: CXCR1
CXCR1
0.010 AlteredExpression disease BEFREE Furthermore, the level of IL-8 and its receptors CXCR1 and CXCR2 expression were associated with ovarian cancer stage, grade and lymph node metastasis. 31793192 2020